LAMTOR2
late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
Synonyms:
ENDAP, HSPC003, MAPBPIP, MAPKSP1AP, ROBLD3, Ragulator2, p14
Species:
Human LAMTOR2 (28956), Mouse Lamtor2 (83409), Rat Lamtor2 (295234), naked mole-rat Lamtor2 (101703739), domestic guinea pig Lamtor2 (100720456), dog LAMTOR2 (480125), Zebrafish lamtor2 (445155), sheep LAMTOR2 (101122907), cow LAMTOR2 (616375), domestic cat LAMTOR2 (101084677)
UniProtKB ID:
Gene ID:
- Human(28956) Summary: The product of this gene is highly conserved with a mouse protein associated with the cytoplasmic face of late endosomes and lysosomes. The mouse protein interacts with MAPK scaffold protein 1, a component of the mitogen-activated protein kinase pathway. In humans, a mutation in this gene has been associated with a primary immunodeficiency syndrome, and suggests a role for this protein in endosomal biogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]
- Mouse(83409) late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
- Rat(295234) late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
- naked mole-rat(101703739) late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
- domestic guinea pig(100720456) late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
- dog(480125) late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
- Zebrafish(445155) late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
- sheep(101122907) late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
- cow(616375) late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
- domestic cat(101084677) late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
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