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DLK1

delta-like 1 homolog (Drosophila)

Synonyms:
DLK, DLK-1, Delta1, FA1, PREF1, Pref-1, ZOG, pG2
Species:
UniProtKB ID:
Gene ID:
  • Human(8788) Summary: This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass. [provided by RefSeq, Mar 2010]
  • Mouse(13386) delta-like 1 homolog (Drosophila)
  • Rat(114587) delta-like 1 homolog (Drosophila)
  • chicken(423459) delta-like 1 homolog (Drosophila)
  • Goat(100860802) delta-like 1 homolog (Drosophila)
  • domestic guinea pig(100719185) delta-like 1 homolog (Drosophila)
  • naked mole-rat(101700819) delta-like 1 homolog (Drosophila)
  • sheep(641301) delta-like 1 homolog (Drosophila)
  • sheep(101119678) delta-like 1 homolog (Drosophila)
  • Horse(100054933) delta-like 1 homolog (Drosophila)
  • cow(281117) delta-like 1 homolog (Drosophila)
  • dog(490860) delta-like 1 homolog (Drosophila)
  • domestic cat(101081814) delta-like 1 homolog (Drosophila)

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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ELISA

Product Number
Description
Species
Human Pref-1 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
ANTI-DLK antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-DLK1 Antibody, clone 3A10, ascites fluid, clone 3A10, from mouse,
Species Reactivity
human, mouse
Application
immunofluorescence
immunohistochemistry
Anti-DLK1 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-DLK1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
western blot
Anti-DLK1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, rat
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human DLK1,
Species
human
MISSION® esiRNA, targeting mouse Dlk1,
Species
mouse