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Merck

ABCB7

ATP-binding cassette, sub-family B (MDR/TAP), member 7

Synonyms:
ABC7, ASAT, Atm1p, EST140535
Species:
UniProtKB ID:
Gene ID:
  • Human(22) Summary: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been associated with mitochondrial iron accumulation and isodicentric (X)(q13) and sideroblastic anemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012]
  • Mouse(11306) ATP-binding cassette, sub-family B (MDR/TAP), member 7
  • Rat(302395) ATP-binding cassette, subfamily B (MDR/TAP), member 7
  • domestic cat(101082805) ATP-binding cassette, sub-family B (MDR/TAP), member 7
  • Horse(100060544) ATP-binding cassette, sub-family B (MDR/TAP), member 7
  • dog(491967) ATP-binding cassette, sub-family B (MDR/TAP), member 7
  • chicken(422326) ATP-binding cassette, sub-family B (MDR/TAP), member 7
  • fruit fly(38193) CG7955 gene product from transcript CG7955-RA
  • Zebrafish(566515) ATP-binding cassette, sub-family B (MDR/TAP), member 7
  • naked mole-rat(101721701) ATP-binding cassette, sub-family B (MDR/TAP), member 7
  • domestic guinea pig(100724759) ATP-binding cassette, sub-family B (MDR/TAP), member 7
  • Domestic Rabbit(100351866) ATP-binding cassette, sub-family B (MDR/TAP), member 7
  • sheep(101113989) ATP-binding cassette, sub-family B (MDR/TAP), member 7
  • cow(533669) ATP-binding cassette, sub-family B (MDR/TAP), member 7

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ABCB7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ABCB7,
Species
human
MISSION® esiRNA, targeting mouse Abcb7,
Species
mouse