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Merck

The concept of an artificial tympanic membrane.

Clinical otolaryngology and allied sciences (1984-08-01)
L Feenstra, F E Kohn, J Feyen
ABSTRACT

A review is given of the development of the concept of an artificial tympanic membrane. Starting with homologous tympanic membranes we compared biodegradable collagen materials (homologous and heterologous) and biodegradable synthetic materials, poly-glycolic acid, poly-lactic acid and poly-alpha-amino acids. As a non-degradable material microporous PTFE and bisphenol-A poly (carbonate) were investigated. It is concluded that either poly-alpha-amino acid or PTFE with poly-alpha-amino acid maybe a suitable material for an artificial tympanic membrane.

MATERIALS
Product Number
Brand
Product Description

Supelco
Poly(Bisphenol A carbonate), analytical standard, molecular weight series
Sigma-Aldrich
Poly(Bisphenol A carbonate), average Mw ~45,000 by GPC
Supelco
Poly(Bisphenol A carbonate), analytical standard
Sigma-Aldrich
Poly(Bisphenol A carbonate), melt index 10-12 g/10 min (300°C/1.2kg)