This product is synthetically produced.
L7900
Sodium DL-lactate solution
synthetic, syrup, BioXtra, suitable for mouse embryo cell culture, 60 % (w/w)
Synonym(s):
DL-Lactic acid sodium salt
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About This Item
Linear Formula:
CH3CH(OH)COONa
CAS Number:
Molecular Weight:
112.06
UNSPSC Code:
12352207
NACRES:
NA.75
PubChem Substance ID:
EC Number:
200-772-0
Beilstein/REAXYS Number:
4332999
MDL number:
Pricing and availability is not currently available.
biological source
synthetic
Quality Level
product line
BioXtra
form
syrup
concentration
60 % (w/w)
technique(s)
cell culture | embryo: suitable
storage temp.
2-8°C
SMILES string
[Na+].CC(O)C([O-])=O
InChI
1S/C3H6O3.Na/c1-2(4)3(5)6;/h2,4H,1H3,(H,5,6);/q;+1/p-1
InChI key
NGSFWBMYFKHRBD-UHFFFAOYSA-M
Application
Lactic acid is an α hydroxyl carboxylic acid produced from pyruvate by the enzyme lactate dehydrogenase (LDH). This mixed isomer lactate has been qualified for use in mouse embryo culture. Lactate regulates pyruvate uptake and metabolism in the preimplantation mouse embryo.
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This Item | |||
|---|---|---|---|
| technique(s) cell culture | embryo: suitable | technique(s) cell culture | mammalian: suitable | technique(s) - | technique(s) mass spectrometry (MS): suitable |
| concentration 60 % (w/w) | concentration 27-33% (enzymatic), 60 % (w/w) | concentration 60 % (w/w) | concentration 45-55 % (w/w) in H2O |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| product line BioXtra | product line BioReagent | product line - | product line - |
| form syrup | form syrup | form syrup | form - |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. −20°C |
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Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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L J Edwards et al.
Molecular reproduction and development, 50(4), 434-442 (1998-07-21)
Although intracellular pH (pHi), is a regulator of numerous biological processes, it has received relatively little attention with regard to the physiology of the mammalian preimplantation embryo. Interestingly, there is some controversy as to whether the early embryo can recover
M Lane et al.
Biology of reproduction, 62(1), 16-22 (1999-12-28)
This study was an investigation of the interaction of lactate on pyruvate and glucose metabolism in the early mouse embryo. Pyruvate uptake and metabolism by mouse embryos were significantly affected by increasing the lactate concentration in the culture medium. In
HiPS-Endothelial Cells Acquire Cardiac Endothelial Phenotype in Co-culture With hiPS-Cardiomyocytes.
Emmi Helle et al.
Frontiers in cell and developmental biology, 9, 715093-715093 (2021-08-24)
Cell-cell interactions are crucial for organ development and function. In the heart, endothelial cells engage in bidirectional communication with cardiomyocytes regulating cardiac development and growth. We aimed to elucidate the organotypic development of cardiac endothelial cells and cardiomyocyte and endothelial
Global Trade Item Number
| SKU | GTIN |
|---|---|
| L7900-100ML | 04061833965788 |
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Is this product produced from Genetically Modified organisms (GMO's)?
1 answer-
Helpful?
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Hi, Could you tell me what is the concentration of the solution in M (or mM) please? Thank you
1 answer-
The concentration of this product changes slightly from lot to lot. A solution of precisely 60% has a molarity of 7.0 M based on a density of 1.31 g/ml and a molecular weight of 112.1. Please see the link below to review a sample Certificate of Analysis:
https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COFA/Q14/L7900-100ML0000229622.pdfHelpful?
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