A2646

D-Arginine

≥98% (TLC), suitable for ligand binding assays

• Synonym(s): (R)-2-Amino-5-guanidinopentanoic acid
• Linear Formula: H₂NC(=NH)NH(CH₂)₃CH(NH₂)CO₂H
• CAS Number: 157-06-2
• Molecular Weight: 174.20
• PubChem Substance ID: 24890684
• eCl@ss: 32160406
• UNSPSC Code: 12352209
• NACRES: NA.32
• EC Number: 205-866-5
• MDL number: MFCD00063116
• Beilstein/REAXYS Number: 1725412

Properties

• Product Name: D-Arginine, ≥98% (TLC)
• Quality Segment: 200
• assay: ≥98% (TLC)
• form: powder
• technique(s): ligand binding assay: suitable
• color: white to off-white
• mp: 226 °C (dec.) (lit.)
• application(s): peptide synthesis
• SMILES string: N[C@H](CCCNC(N)=N)C(O)=O
• InChI: 1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t4-/m1/s1
• InChI key: ODKSFYDXXFIFQN-SCSAIBSYSA-N
• Gene Information: rat ... Ppm1a(24666)

Description

General description

Arginine (Arg) is a dibasic amino acid and exists as two enantiomers: D-Arg and L-Arg. D-Arg is a cationic endogenous amino acid and is found in the central nervous system.[1]

Application

D-Arginine has been used:

• as an organic substrate to study the metabolic versatility of freshwater sedimentary archaea feeding on different organic carbon sources[2]
• to study its role in the inhibition of Pseudorabies virus (PRV) plaque formation by arginase[3]
• as a reference standard for chromatographic separation[4]

Biochem/physiol Actions

D-Arginine is a semi-essential amino acid that maintains cell death in the central nervous system (CNS). It may possess neuroprotective actions against glucocorticoids induced neurotoxicity in the CNS.[1]

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves