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Key Documents

Y0001521

Amoxicillin trihydrate for performance verification

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Amoxicillin trihydrate

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About This Item

Empirical Formula (Hill Notation):
C16H19N3O5S · 3H2O
CAS Number:
Molecular Weight:
419.45
Beilstein:
7507120
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

amoxicillin

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

O.O.O.CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccc(O)cc3)C(=O)N2[C@H]1C(O)=O

InChI

1S/C16H19N3O5S.3H2O/c1-16(2)11(15(23)24)19-13(22)10(14(19)25-16)18-12(21)9(17)7-3-5-8(20)6-4-7;;;/h3-6,9-11,14,20H,17H2,1-2H3,(H,18,21)(H,23,24);3*1H2/t9-,10-,11+,14-;;;/m1.../s1

InChI key

MQXQVCLAUDMCEF-CWLIKTDRSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Amoxicillin trihydrate for performance verification EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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Product No.
Description
Pricing

Pictograms

Health hazard

Signal Word

Danger

Hazard Statements

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Development and Validation of RP-HPLC Method for Simultaneous Estimation of Amoxicillin trihydrate and Flucloxacillin sodium in capsule dosage form.
Nikam.S D, et al.
International Journal of PharmTech Research, 1(3), 935-939 (2009)
Clinical trial evidence to advance the science of cholecystectomy.
Joseph S Solomkin
JAMA, 312(2), 135-136 (2014-07-10)
Gilson C N Franco et al.
International journal of clinical pharmacology and therapeutics, 52(5), 425-430 (2014-04-24)
To compare the pharmacokinetic profiles and to evaluate the bioequivalence of two commercial amoxicillin suspension formulations (500 mg/5 mL AMOXIL®, reference formulation and AMOXI-PED®, test formulation) in healthy Brazilian volunteers. Under fasting condition, 25 volunteers (13 males and 12 females)
Jean Marc Regimbeau et al.
JAMA, 312(2), 145-154 (2014-07-10)
Ninety percent of cases of acute calculous cholecystitis are of mild (grade I) or moderate (grade II) severity. Although the preoperative and intraoperative antibiotic management of acute calculous cholecystitis has been standardized, few data exist on the utility of postoperative
In acute calculous cholecystitis, antibiotics after cholecystectomy did not reduce infection.
Daniel I Steinberg
Annals of internal medicine, 161(12), JC4-JC4 (2014-12-17)

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