Skip to Content
Merck
All Photos(4)

Key Documents

05-1567

Sigma-Aldrich

Anti-p120 Catenin Antibody, clone 15D2

clone 15D2, from mouse

Synonym(s):

Cadherin-associated Src substrate, catenin (cadherin-associated protein), delta 1, catenin, delta 1, p120 catenin

Sign Into View Organizational & Contract Pricing


About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

purified antibody

antibody product type

primary antibodies

clone

15D2, monoclonal

species reactivity

mouse, human

species reactivity (predicted by homology)

rat

technique(s)

flow cytometry: suitable
immunocytochemistry: suitable
western blot: suitable

isotype

IgG1κ

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... CTNND1(1500)

General description

p120 Catenin is a cadherin-associated protein that binds intracellular proteins, such as the small GTPase, RhoA, and controls E-cadherin funcation and stability. Proteins of the p120 family and their isoforms are expressed in cells via alternative splicing, and all of them are essential for HGF signaling to Rac1.

Specificity

Recognizes p120 Catenin

Immunogen

Epitope: C-terminus
Recombinant fusion protein derived from the C-terminus of murine p120

Application

Immunocytochemistry:
Research Category
Signaling
Research Sub Category
Transcription Factors
Use Anti-p120 Catenin Antibody, clone 15D2 (mouse monoclonal antibody) validated in WB, ICC, FC to detect p120 Catenin also known as Cadherin-associated Src substrate ,catenin (cadherin-associated protein) delta 1.

Quality

Evaluated by Western Blot on Hela cell lysate.
Western Blot Analysis: 1 g/mL of this antibody detected p120 Catenin in lysate from Hela cells.

Target description

90-120 kDa

Linkage

Replaces: 04-237

Physical form

Format: Purified
Protein G Chromatography
Purified mouse monoclonal in 0.1M Tris-Glycine (pH 7.4), 150mM NaCl and 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8ºC from date of receipt.
Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution.

Analysis Note

Control
Hela cell lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Not finding the right product?  

Try our Product Selector Tool.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Hiromi Sato et al.
PLoS neglected tropical diseases, 11(7), e0005830-e0005830 (2017-07-28)
Pathogenic Leptospira transmits from animals to humans, causing the zoonotic life-threatening infection called leptospirosis. This infection is reported worldwide with higher risk in tropical regions. Symptoms of leptospirosis range from mild illness to severe illness such as liver damage, kidney
Dulari Jayawardena et al.
Cellular and molecular gastroenterology and hepatology, 15(4), 903-919 (2022-12-20)
Down-regulation of chloride transporter SLC26A3 or down-regulated in adenoma (DRA) in colonocytes has recently been linked to the pathogenesis of ulcerative colitis (UC). Because exaggerated immune responses are one of the hallmarks of UC, these current studies were undertaken to
Lorena de la Fuente et al.
Genome biology, 21(1), 119-119 (2020-05-20)
Recent advances in long-read sequencing solve inaccuracies in alternative transcript identification of full-length transcripts in short-read RNA-Seq data, which encourages the development of methods for isoform-centered functional analysis. Here, we present tappAS, the first framework to enable a comprehensive Functional
Lindy J Pence et al.
International journal of molecular sciences, 22(3) (2021-02-03)
Inflammatory breast cancer is a highly aggressive form of breast cancer that forms clusters of tumor emboli in dermal lymphatics and readily metastasizes. These cancers express high levels of E-cadherin, the major mediator of adherens junctions, which enhances formation of
Joyce Nair-Menon et al.
International journal of molecular sciences, 21(7) (2020-04-11)
The RNA interference (RNAi) machinery is an essential component of the cell, regulating miRNA biogenesis and function. RNAi complexes were thought to localize either in the nucleus, such as the microprocessor, or in the cytoplasm, such as the RNA-induced silencing

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service