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850090P

Avanti

Soy Lyso PI

Avanti Research™ - A Croda Brand 850090P, powder

Synonym(s):

L-α-lysophosphatidylinositol (Soy) (sodium salt)

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About This Item

CAS Number:
796963-91-2
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (LPI; may contain up to 10% of the 2-LPI isomer, TLC)

form

powder

packaging

pkg of 1 × 10 mg (850090P-10mg)
pkg of 1 × 5 mg (850090P-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 850090P

lipid type

phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

Application

Soy Lyso PI or L-α-lysophosphatidylinositol (Soy) (sodium salt) has been used:
  • in giant unilamellar vesicles (GUVs), to measure the effect of LysoPI on membrane bending rigidity
  • as an exogenous lysophospholipid to study its effect on clathrin-dependent endocytosis
  • as a substrate to measurement the glycerophosphodiester phosphodiesterases (GP-PDE) and lysophospholipase D activities of the two recombinant mouse GDE4 and GDE7 proteins

Biochem/physiol Actions

Lysophosphatidylinositol (LPI) is a bioactive lipid, involved as a signaling mediator in many biological events. It controls cell growth, differentiation and motility. LPI is associated with pathological processes such as cancer cell proliferation.

Packaging

5 mL Amber Glass Screw Cap Vial (850090P-10mg)
5 mL Amber Glass Screw Cap Vial (850090P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Noriyasu Ohshima et al.
The Journal of biological chemistry, 290(7), 4260-4271 (2014-12-22)
The known mammalian glycerophosphodiester phosphodiesterases (GP-PDEs) hydrolyze glycerophosphodiesters. In this study, two novel members of the mammalian GP-PDE family, GDE4 and GDE7, were isolated, and the molecular basis of mammalian GP-PDEs was further explored. The GDE4 and GDE7 sequences are
Syamsul A Arifin et al.
Metabolites, 6(1) (2016-01-20)
Metabolism is a chemical process used by cells to transform food-derived nutrients, such as proteins, carbohydrates and fats, into chemical and thermal energy. Whenever an alteration of this process occurs, the chemical balance within the cells is impaired and this
Alejandro Melero et al.
Current biology : CB, 28(12), 1950-1958 (2018-06-12)
Coat protein complex II (COPII) proteins form vesicles from the endoplasmic reticulum to export cargo molecules to the Golgi apparatus. Among the many proteins involved in this process, Sec12 is a key regulator, functioning as the guanosine diphosphate (GDP) exchange
Ieva Ailte et al.
Traffic (Copenhagen, Denmark), 18(3), 176-191 (2017-01-10)
In this study, we have investigated how clathrin-dependent endocytosis is affected by exogenously added lysophospholipids (LPLs). Addition of LPLs with large head groups strongly inhibits transferrin (Tf) endocytosis in various cell lines, while LPLs with small head groups do not.

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