Skip to Content
Merck
All Photos(1)

Key Documents

MX1394

Supelco

NMP

for Peptide Synthesis

Synonym(s):

1-Methyl-2-Pyrrolidone, 1-Methyl-2-pyrrolidinone,NMP

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
(CH3)-NC(=O)CH2CH2CH2-
CAS Number:
MDL number:
UNSPSC Code:
12352115
EC Index Number:
212-828-1

product name

1-Methyl-2-pyrrolidone, for Peptide Synthesis

vapor pressure

0.32 hPa ( 20 °C)

Quality Level

Assay

≥99.5% (GC)

form

liquid

impurities

≤1 ppm Heavy metals (as Pb)
≤1.0 μeq/g Titrable base
≤300 ppm Water (H2O)
≤5 ppm Free amine (as dimethylamine)

color

clearAPHA: ≤20

pH

8.5-10.0 (20 °C, 100 g/L in H2O)

bp

202 °C/1013 hPa

mp

-24 °C

transition temp

flash point 91 °C

solubility

1000 g/L

density

1.03 g/cm3 at 20 °C

UV cutoff

≤275 nm

UV absorption

λ: 275 nm Amax: ≤1.00
λ: 280 nm Amax: ≤0.70
λ: 300 nm Amax: ≤0.30
λ: 350 nm Amax: ≤0.10
λ: 400 nm Amax: ≤0.01

application(s)

peptide synthesis

shipped in

ambient

storage temp.

room temp

InChI

1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3

InChI key

SECXISVLQFMRJM-UHFFFAOYSA-N

Application

for Peptide Synthesis

Preparation Note

Product filtered through a 0.2 μm filter

Analysis Note

AppearanceClear, free from particulatesAssay (GC)99.5% minColor (APHA)20 maxFiltered through 0.2 µm filterTo pass testFormLiquidFree amine (as dimethylamine)5ppm maxHeavy metals (as Pb)1ppm maxResidue after ignition10ppm maxTitrable base1.0µeq/g maxUV Abs. at 275 nm1.00AU maxUV Abs. at 280 nm0.70AU maxUV Abs. at 300 nm0.30AU maxUV Abs. at 350 nm0.10AU maxUV Abs. at 400 nm0.01AU maxUV Cut-off275nm maxWater (H2O)300ppm max

Pictograms

Health hazardExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

Flash Point(F)

195.8 °F - Pensky-Martens closed cup

Flash Point(C)

91 °C - Pensky-Martens closed cup


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service