Raman spectra of methyl substituted benz[c]acridines and their complex with DNA.

Raman spectra of methyl substituted benz[c]acridines (BAc) in the solid state were recorded. Their assignments were proposed for the frequencies of Raman spectra observed. The purpose of this work was to elucidate the mechanisms of interaction between BAc and DNA in vitro. For the DNA-BAc complex, the data show that BAc interact not only with the bases pair, but also with the sugar-phosphate site of DNA within the interbinding process.