SAB4502615

Anti-NF-κB p65 antibody produced in rabbit

affinity isolated antibody

• Synonym(s): NFKB3, RELA, TF65, nuclear factor NF-κ-B p65 subunit, p65
• MDL number: MFCD00802848
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 60 kDa
• species reactivity: human, rat, mouse
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:5000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI accession no.: Q04206
• UniProt accession no.: Q04206
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... RELA(5970)

Description

General description

Anti-NF-κB p65 Antibody detects endogenous levels of total NF-κB p65 protein.

RELA (v-rel avian reticuloendotheliosis viral oncogene homolog A), also known as nuclear factor κ-B (NF-κ-B) p65 subunit, codes for an important constituent of the NF-κB complex. The gene encoding it is localized on human chromosome 11q13.1. It is also referred as nuclear factor κB subunit 3 (NFκB3).

Immunogen

The antiserum was produced against synthesized peptide derived from human NF-kappaB p65.

Immunogen Range: 247-296

Application

Anti-NF-κB p65 antibody produced in rabbit is used in Western Blotting.

Biochem/physiol Actions

RELA (v-rel avian reticuloendotheliosis viral oncogene homolog A) or nuclear factor NF-κ-B p65 subunit participates in the nuclear factor κ-B (NFκB) signaling pathway. It also modulates inflammation. Alterations in the gene have been linked to schizophrenia and startle reactions.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable