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C2288

Sigma-Aldrich

Anti-Chicken IgY (IgG) (whole molecule) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Rabbit Anti-Chicken IgY (IgG) (whole molecule)

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About This Item

MDL number:
UNSPSC Code:
12352203
NACRES:
NA.46

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

secondary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

chicken

technique(s)

indirect ELISA: 1:25,000

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

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General description

The product binds to chicken IgY (IgG).

Application

Anti-Chicken IgY (IgG) (whole molecule) antibody produced in rabbit has been used in enzyme linked immuno sorbent assay (ELISA).

Biochem/physiol Actions

IgY antibody subtype is the most abundant of serum immunoglobulins of the immune system in birds and is analogous to IgG found in mammals. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Storage and Stability

For continuous use, store at 2-8 °C for up to one month. For extended storage, the solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. Storage in "frost-free" freezers not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Vincenzo Di Cerbo et al.
eLife, 3, e01632-e01632 (2014-03-29)
Post-translational modifications of proteins have emerged as a major mechanism for regulating gene expression. However, our understanding of how histone modifications directly affect chromatin function remains limited. In this study, we investigate acetylation of histone H3 at lysine 64 (H3K64ac)
Cecilia Rengifo Rojas et al.
HGG advances, 5(2), 100271-100271 (2024-02-01)
It is only partially understood how constitutive allelic methylation at imprinting control regions (ICRs) interacts with other regulation levels to drive timely parental allele-specific expression along large imprinted domains. The Peg13-Kcnk9 domain is an imprinted domain with important brain functions.
Chickens with humanized immunoglobulin genes generate antibodies with high affinity and broad epitope coverage to conserved targets
Ching KH, et al.
MAbs, 10(1), 71-80 (2018)
A Larsson et al.
Poultry science, 72(10), 1807-1812 (1993-10-01)
Laying hens are highly cost-effective as producers of antibodies compared with the mammals traditionally used for such production. Also, chicken antibodies have biochemical advantages over mammalian antibodies due to the phylogenetical differences between avian and mammalian species, resulting in increased
Kathryn H Ching et al.
mAbs, 10(1), 71-80 (2017-10-17)
Transgenic animal platforms for the discovery of human monoclonal antibodies have been developed in mice, rats, rabbits and cows. The immune response to human proteins is limited in these animals by their tolerance to mammalian-conserved epitopes. To expand the range

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