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34084

Supelco

Flocoumafen

PESTANAL®, analytical standard

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About This Item

Empirical Formula (Hill Notation):
C33H25F3O4
CAS Number:
Molecular Weight:
542.54
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

description

mixture of isomers

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

SMILES string

OC1=C(C2CC(Cc3ccccc23)c4ccc(OCc5ccc(cc5)C(F)(F)F)cc4)C(=O)Oc6ccccc16

InChI

1S/C33H25F3O4/c34-33(35,36)24-13-9-20(10-14-24)19-39-25-15-11-21(12-16-25)23-17-22-5-1-2-6-26(22)28(18-23)30-31(37)27-7-3-4-8-29(27)40-32(30)38/h1-16,23,28,37H,17-19H2

InChI key

KKBGNYHHEIAGOH-UHFFFAOYSA-N

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General description

Flocoumafen is a second generation anticoagulant rodenticides, which can have an array of applications in pest control.(1) It belongs to the 4-hydroxycoumarin class of rodenticides.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 1B - STOT RE 1

Target Organs

Blood

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

73.4 °F

Flash Point(C)

23 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number

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Mi-Cong Jin et al.
Rapid communications in mass spectrometry : RCM, 20(18), 2741-2746 (2006-08-22)
A rapid, sensitive and selective method for the simultaneous determination of bromadiolone, flocoumafen and brodifacoum in whole blood using warfarin as internal standard (IS) by high-performance liquid chromatography coupled with electrospray ionization mass spectrometry (HPLC/ESI-MS) has been developed and validated.
K R Huckle et al.
Xenobiotica; the fate of foreign compounds in biological systems, 18(12), 1465-1479 (1988-12-01)
1. Following multiple oral administration of 14C-flocoumafen to rats at 0.02 and 0.1 mg/kg per week, appreciable cellular accumulation was seen in the liver. 2. Residues in the liver increased with dose throughout the duration of the experiment (14 weeks)
Steffen Boettcher et al.
European journal of haematology, 86(2), 173-175 (2010-11-10)
A 28 year-old heretofore healthy woman was transferred to our hospital with a two-month history of recurring episodes of bleeding. Administration of vitamin K and prothrombin complex concentrates in the transferring hospital had only temporarily corrected both the markedly elevated
V R Parshad et al.
The Journal of hygiene, 96(3), 475-478 (1986-06-01)
The anticoagulant rodenticide flocoumafen was evaluated against Rattus rattus and Bandicota bengalensis. In no-choice 24 h feeding tests 100% mortality occurred at 0.00125% concentration of the poison in the bait in the case of B. bengalensis and at 0.00375% in
Mi-Cong Jin et al.
Journal of applied toxicology : JAT, 27(1), 18-24 (2006-12-21)
A high-performance liquid chromatographic-tandem mass spectrometric (HPLC-MS-MS) assay was developed and validated to determine quantitatively flocoumafen and brodifacoum in whole blood using warfarin as an internal standard (IS). Liquid-liquid extraction, using ethyl acetate, was used to isolate flocoumafen, brodifacoum and

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