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435015

Sigma-Aldrich

Methyl 2-hydroxyethyl cellulose

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About This Item

CAS Number:
9032-42-2
MDL number:
MFCD00147597
UNSPSC Code:
12162002
NACRES:
NA.23

extent of labeling

0.06-0.50 mol hydroxyethyl per mol cellulose (M.S.)
8 wt. % hydroxyethyl
26 wt. % methoxy
1.3-2.2 mol methyl per mol cellulose (D.S.)

surface tension

45-55 dyn/cm, 20 °C, 0.1 wt. %

viscosity

15,000-20,500 cP, 2 wt. % in H2O(20 °C, Brookfield, spindle #6) (20 rpm)(lit.)

transition temp

flocculation range 60-90 °C (0.5 wt. %)

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Application

Water retention aid, thickening agent, protective colloid, suspending agent, binder and stabilizer.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Rondedrick Sinville et al.
Electrophoresis, 29(23), 4751-4760 (2008-12-05)
We have developed a new method for the analysis of low abundant point mutations in genomic DNA using a combination of an allele-specific ligase detection reaction (LDR) with free-solution conjugate electrophoresis (FSCE) to generate and analyze the genetic products. FSCE
K M Picker et al.
Pharmaceutical development and technology, 3(1), 31-41 (1998-04-09)
The aim of this research was to investigate the elastic-plastic deformation behavior of the cellulose ethers hydroxypropylmethylcellulose (HPMC), hydroxyethylmethylcellulose (HEMC), and sodium carboxymethylcellulose (NaCMC) at relative humidities (RH) of 38, 57, and 75% and assess how the release of drugs
M G Lee
Journal of clinical and hospital pharmacy, 7(1), 67-70 (1982-03-01)
A method is reported for the analysis of prostaglandin PGE2 in methylhydroxyethylcellulose gel. Stability studies using the method have shown that the degradation of PGE in the gel is a first order process at 4 degrees and 25 degrees C.
Roland Adden et al.
Analytical chemistry, 78(4), 1146-1157 (2006-02-16)
Hydroxyethylmethyl celluloses (HEMC, DS(Me) 1.46-1.66, DS(HE) = 0.14-0.17) have been analyzed with respect to their methyl and hydroxyethyl pattern in the glucosyl units and along the polymer chain. Methyl groups were located by GLC/MS after direct hydrolysis, reduction, and acetylation
S Zuleger et al.
International journal of pharmaceutics, 217(1-2), 139-152 (2001-04-09)
The present study deals with controlled drug delivery from hydrocolloid tablets by polymer particle erosion. The influence of excipients and formulation factors on the dissolution behaviour of the methyl hydroxyethyl cellulose (MHEC)-tablets is investigated. Linear drug release with low susceptibility
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