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419753

Sigma-Aldrich

7-Hydroxyflavanone

98%

Synonym(s):

7-Hydroxy-2-phenylchroman-4-one

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About This Item

Empirical Formula (Hill Notation):
C15H12O3
CAS Number:
6515-36-2
Molecular Weight:
240.25
MDL number:
MFCD00017487
UNSPSC Code:
12352100
PubChem Substance ID:
24866274
NACRES:
NA.22

Assay

98%

form

solid

mp

188-190 °C (lit.)

SMILES string

Oc1ccc2C(=O)CC(Oc2c1)c3ccccc3

InChI

1S/C15H12O3/c16-11-6-7-12-13(17)9-14(18-15(12)8-11)10-4-2-1-3-5-10/h1-8,14,16H,9H2

InChI key

SWAJPHCXKPCPQZ-UHFFFAOYSA-N

Gene Information

mouse ... Maoa(17161)
rat ... Aldh1a2(116676)

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Application

7-Hydroxyflavanone has been used for the stereoisomeric separation of flavonoids using polysaccharide-based chiral stationary phases by nano-liquid chromatography (nano-LC).

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Tomasz Wróblewski et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 215, 81-87 (2019-03-02)
In this work the photophysical properties of 7-hydroxyflavanone in acetonitrile, ethanol and methanol have been studied. The quantum chemical calculations as well as the experimental measurements have been performed. The absorption and emission spectra have been obtained for 7-hydroxyflavanone dissolved
F R Cross
Journal of cell science. Supplement, 12, 117-127 (1989-01-01)
The DAF1-1 mutation reduces cell size and reduces or eliminates G1 phase in Saccharomyces cerevisiae, and results in alpha-factor resistance. DAF1-1 cells transferred into low cycloheximide express an increased G1 phase in their cycle, suggesting that G1 regulation is present
Přemysl Mladěnka et al.
Journal of inorganic biochemistry, 105(5), 693-701 (2011-04-01)
Flavonoids have been demonstrated to possess miscellaneous health benefits which are, at least partly, associated with iron chelation. In this in vitro study, 26 flavonoids from different subclasses were analyzed for their iron chelating activity and stability of the formed
[Microbial kinetics: experiences with Staphylococcus aureus ATCC 25 293 and bacteriostatic drugs].
N B Pappano et al.
Revista latinoamericana de microbiologia, 29(4), 367-372 (1987-10-01)
Julie Rakel Mikell et al.
Chemical & pharmaceutical bulletin, 60(9), 1139-1145 (2012-09-15)
Microbial metabolism of 7-hydroxyflavanone (1) with fungal culture Cunninghamella blakesleeana (ATCC 8688a), yielded flavanone 7-sulfate (2), 7,4'-dihydroxyflavanone (3), 6,7-dihydroxyflavanone (4), 6-hydroxyflavanone 7-sulfate (5), and 7-hydroxyflavanone 6-sulfate (6). Mortierella zonata (ATCC 13309) also transformed 1 to metabolites 2 and 3 as
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