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Merck

Cosmeceuticals: the evidence behind the retinoids.

Aesthetic surgery journal (2010-05-06)
Kajal Babamiri, Reza Nassab
ABSTRACT

A wide range of cosmeceutical products are available on the market currently, but evidence to support their use is often lacking in the literature. Specifically, there is a substantial amount of evidence supporting the efficacy of tretinoin in photoaging, but the evidence supporting retinoid-based cosmeceuticals remains sparse. The authors review the current data in the literature related to vitamin A-derived cosmeceutical products and conclude that cosmeceuticals containing retinaldehyde have been shown in large randomized, controlled trials to have the most beneficial effect on aging skin.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Retinyl palmitate, Type IV, ~1,800,000 USP units/g, oil
Supelco
Retinyl Acetate (Vitamin A Acetate), Pharmaceutical Secondary Standard; Certified Reference Material
Sigma-Aldrich
Retinyl acetate, synthetic, matrix dispersion, 475,000-650,000 USP units/g
Sigma-Aldrich
Retinyl acetate, synthetic, crystalline solid or supercooled liquid
Sigma-Aldrich
Retinyl acetate, BioReagent, solid or viscous liquid, synthetic, suitable for cell culture
Retinol acetate, European Pharmacopoeia (EP) Reference Standard
Supelco
Retinyl acetate, analytical standard