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Key Documents

P2516

Sigma-Aldrich

Plasma

from rat

Synonym(s):

Citrated plasma

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About This Item

MDL number:
UNSPSC Code:
12352207
NACRES:
NA.71

biological source

rat

Quality Level

form

powder

contains

3.8% trisodium citrate as anticoagulant

storage temp.

2-8°C

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General description

Plasma is straw yellow in color and is the liquid portion of blood. The major component of plasma is water with solids accounting to 9%.

Biochem/physiol Actions

Plasma comprises many proteins that regulate various biological functions including electrolyte balance, transport and defense. Infusion of plasma by therapeutic plasmapheresis is useful in treating illness. However, at the same time it triggers allergic reactions.

Other Notes

This product is prepared from pooled rat blood. It contains 3.8% trisodium citrate as an anticoagulant. It is tested for clotting, which indicates that the clotting factors in the product are active. However, it is not analyzed to determine whether other enzymes present are native or denatured. The resulting plasma is 0.45 microm filtered and lyophilized from the indicated volume.

Preparation Note

Whole blood collected with anticoagulants (9:1), pooled, and centrifuged. The resulting plasma is 0.45 μm filtered and lyophilized from the indicated volumes.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Plasma and Plasma proteins
Essentials of Medical physiology (2018)
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Clinical proteomics, 17, 33-33 (2020-09-24)
Verification of cerebrospinal fluid (CSF) biomarkers for multiple sclerosis and other neurological diseases is a major challenge due to a large number of candidates, limited sample material availability, disease and biological heterogeneity, and the lack of standardized assays. Furthermore, verification
Plasma and plasma derivatives in therapeutic plasmapheresis
McLeod, Bruce C
Transfusion, 52, 38S-44S (2012)
A I Potapovich et al.
British journal of pharmacology, 158(5), 1236-1247 (2009-09-30)
The immunomodulatory effects of alpha-fetoprotein (AFP) on lymphocytes and macrophages have been described in vitro and in vivo. Recombinant forms of human AFP have been proposed as potential therapeutic entities for the treatment of autoimmune diseases. We examined the effects

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