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S607

Sigma-Aldrich

Salicylhydroxamic acid

99%

Synonym(s):

2-Hydroxybenzohydroxamic acid, N,2-Dihydroxybenzamide

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About This Item

Linear Formula:
HOC6H4CONHOH
CAS Number:
Molecular Weight:
153.14
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

99%

mp

177 °C (dec.) (lit.)

SMILES string

ONC(=O)c1ccccc1O

InChI

1S/C7H7NO3/c9-6-4-2-1-3-5(6)7(10)8-11/h1-4,9,11H,(H,8,10)

InChI key

HBROZNQEVUILML-UHFFFAOYSA-N

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Application

Salicylhydroxamic acid can be used:
  • To prepare phenylboronic acid-based bioconjugates for chromatographic applications.
  • As a ligand to synthesize Fe(III), Cu(II), Ni(II) and Zn(II) complexes.
  • As a selective collector in the segregation of oxide minerals using the flotation method. 

Pictograms

Health hazardExclamation mark

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Solomon Stonebloom et al.
Plant physiology, 158(1), 190-199 (2011-11-15)
Recent studies suggest that intercellular transport via plasmodesmata (PD) is regulated by cellular redox state. Until now, this relationship has been unclear, as increased production of reactive oxygen species (ROS) has been associated with both increased and decreased intercellular transport
Metal complexes of salicylhydroxamic acid (H2Sha), anthranilic hydroxamic acid and benzohydroxamic acid. Crystal and molecular structure of [Cu (phen) 2 (Cl)] Cl . H2Sha, a model for a peroxidase-inhibitor complex
O'Brien EC, et al.
Journal of Inorganic Biochemistry, 79(1-4), 47-51 (2000)
Ayodeji S Owati et al.
Frontiers in plant science, 8, 1165-1165 (2017-07-18)
Ascochyta blight (AB) of pulse crops (chickpea, field pea, and lentils) causes yield loss in Montana, where 1.2 million acres was planted to pulses in 2016. Pyraclostrobin and azoxystrobin, quinone outside inhibitor (QoI) fungicides, have been the choice of farmers
A visualization method for studying the adsorption of lead species in salicylhydroxamic acid flotation of hemimorphite
Zhao W, et al.
Minerals Engineering, 154, 106434-106434 (2020)
Juan F Quintana et al.
PLoS neglected tropical diseases, 14(7), e0008458-e0008458 (2020-07-10)
Defining mode of action is vital for both developing new drugs and predicting potential resistance mechanisms. Sensitivity of African trypanosomes to pentamidine and melarsoprol is predominantly mediated by aquaglyceroporin 2 (TbAQP2), a channel associated with water/glycerol transport. TbAQP2 is expressed

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