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T4009

Taurocholic acid sodium salt hydrate

≥95% (HPLC)

Synonym(s):

2-[(3α,7α,12α-Trihydroxy-24-oxo-5β-cholan-24-yl)amino]ethanesulfonic acid, 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid N-(2-sulfoethyl)amide, Sodium taurocholate hydrate

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Size/SKUAvailabilityPrice
250 mg

Available to ship TODAYfromMILWAUKEE

$38.30
1 g

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$65.80
5 g

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$215.00
25 g

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$814.00
100 g

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$2,410.00

About This Item

Empirical Formula (Hill Notation):
C26H44NNaO7S · xH2O
CAS Number:
Molecular Weight:
537.68 (anhydrous basis)
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12161900
EC Number:
205-653-7
MDL number:

$38.30


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biological source

synthetic (organic)

Quality Segment

description

anionic

assay

≥95% (HPLC)

form

powder

mol wt

micellar avg mol wt 2100

aggregation number

4

CMC

3-11 mM (20-25°C)

functional group

sulfonic acid

shipped in

ambient

storage temp.

room temp

SMILES string

[Na+].[H]O[H].[H][C@@]12C[C@H](O)CC[C@]1(C)[C@@]3([H])C[C@H](O)[C@]4(C)[C@H](CC[C@@]4([H])[C@]3([H])[C@H](O)C2)[C@H](C)CCC(=O)NCCS([O-])(=O)=O

InChI

1S/C26H45NO7S.Na.H2O/c1-15(4-7-23(31)27-10-11-35(32,33)34)18-5-6-19-24-20(14-22(30)26(18,19)3)25(2)9-8-17(28)12-16(25)13-21(24)29;;/h15-22,24,28-30H,4-14H2,1-3H3,(H,27,31)(H,32,33,34);;1H2/q;+1;/p-1/t15-,16+,17-,18-,19+,20+,21-,22+,24+,25+,26-;;/m1../s1

InChI key

RDAJAQDLEFHVNR-NEMAEHQESA-M

General description

Taurocholic acid sodium salt hydrate is a bile acid with detergent capabilities.

Application

Anionic detergent used for protein solubilization.
Taurocholic acid sodium salt hydrate has been used in a study to assess the adsorption of bile acids and salts to vegetable fibrous tissue. [1] It has also been used in a study to investigate a method for determination of conjugated and unconjugated bile salts in serum and jejunal fluid. [2]

Biochem/physiol Actions

Non-sulfated bile salt, physiological transport substrate for the bile salt export pump/sister of Pgp (BSEP/spgp), Na(+)/taurocholate cotransporter (NTCP) and MRP3 into the hepatic carnalicular.
Non-sulfated bile salt.

Preparation Note

Synthesized from cholic acid

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T9034T6260T0557
form

powder

form

powder

form

powder

form

-

assay

≥95% (HPLC)

assay

≥95% (HPLC)

assay

≥95.0% (TLC)

assay

≥97% (TLC)

aggregation number

4

aggregation number

4

aggregation number

-

aggregation number

6

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

storage temp.

-

mol wt

micellar avg mol wt 2100

mol wt

micellar avg mol wt 2100

mol wt

521.69 g/mol

mol wt

micellar avg mol wt 3100

description

anionic

description

anionic

description

anionic

description

anionic


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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