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SRP0451

Sigma-Aldrich

BRD2 (65-187) GST tag human

recombinant, expressed in E. coli, ≥81% (SDS-PAGE)

Synonym(s):

FSH, NAT, RING3, RNF3, bromodomain containing 2

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.32

biological source

human

recombinant

expressed in E. coli

assay

≥81% (SDS-PAGE)

form

aqueous solution

mol wt

41.4 kDa

packaging

pkg of 100 μg

NCBI accession no.

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... BRD2(6046)

General description

Human Bromodomain containing 2, also known as BRD2, RING3 or RNF3 (GenBank Accession No. NM_005104) amino-acids 65 – 187 with N-terminal GST-tag, MW = 41.4 kDa, expressed in an E. coli expression system.

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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Takashi Umehara et al.
FEBS letters, 584(18), 3901-3908 (2010-08-17)
The BET family proteins recognize acetylated chromatin through their two bromodomains, acting as transcriptional activators or tethering viral genomes to the mitotic chromosomes of their host. The structural mechanism for how the N-terminal bromodomain of human BRD2 (BRD2-BD1) deciphers the
Enyuan Shang et al.
Journal of cellular biochemistry, 112(10), 2784-2793 (2011-05-25)
The human BRD2 gene has been linked and associated with a form of common epilepsy and electroencephalographic abnormalities. Disruption of Brd2 in the mouse revealed that it is essential for embryonic neural development and that viable Brd2(+/-) heterozygotes show both

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