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SML3409

ATN-224

≥95% (elemental analysis), SOD1 inhibitor, powder

Synonym(s):

2-hydroxy-N,N,N-trimethylethanaminium tetrathiomolybdate, ALXN1840, Bis-Choline-Tetrathiomolybdate, Tiomolibdate Choline, WTX101

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About This Item

Empirical Formula (Hill Notation):
C10H28N2O2 · MoS4
CAS Number:
Molecular Weight:
432.54
NACRES:
NA.77
UNSPSC Code:
12352200
MDL number:
Assay:
≥95% (elemental analysis)
Form:
powder
Storage condition:
desiccated
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Product Name

ATN-224, ≥95% (elemental analysis)

Quality Segment

assay

≥95% (elemental analysis)

form

powder

storage condition

desiccated

color

, Orange to very dark red

solubility

H2O: ≥0.1 mg/mL, clear

storage temp.

-10 to -25°C

SMILES string

S=[Mo]([S-])([S-])=S.C[N+](C)(CCO)C.C[N+](C)(CCO)C

InChI

1S/2C5H14NO.Mo.4S/c2*1-6(2,3)4-5-7;;;;;/h2*7H,4-5H2,1-3H3;;;;;/q2*+1;;;;2*-1

InChI key

NEYVHGQOGHJAAD-UHFFFAOYSA-N

Biochem/physiol Actions

ATN-224 (Bis-Choline-Tetrathiomolybdate) is an orally available and potent inhibitor of superoxide dismutase 1 (SOD1) that exhibit potent anticancer activities. ATN-224 is a copper chelator that rapidly lowers free coper levels and improve clinical symptoms in Wilson′s disease patients.
Inhibitor of superoxide dismutase 1 (SOD1); Reactive oxygen species (ROS) scavenging blocker

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This Item
323446SML2079615528
description

≥95% (elemental analysis)

description

99.97% trace metals basis

description

≥98% (HPLC)

description

98 atom % D

assay

≥95% (elemental analysis)

assay

99.97% trace metals basis

assay

≥98% (HPLC)

assay

-

form

powder

form

crystalline

form

powder

form

solid

Quality Level

100

Quality Level

200

Quality Level

-

Quality Level

-

storage temp.

-10 to -25°C

storage temp.

-

storage temp.

−20°C

storage temp.

-

storage condition

desiccated

storage condition

-

storage condition

-

storage condition

-

solubility

H2O: ≥0.1 mg/mL, clear

solubility

-

solubility

-

solubility

-


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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