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SML3018

TH1834

≥98% (HPLC)

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Synonym(s):

2-(5-(4-((Phenethyl(4-(4-(pyrrolidin-1-ylmethyl)phenoxy)butyl)amino)methyl)phenyl)-2H-tetrazol-2-yl)acetic acid dihydrochloride, 2H-Tetrazole-2-acetic acid, 5-[4-[[(2-phenylethyl)[4-[4-(1-pyrrolidinylmethyl)phenoxy]butyl]amino]methyl]phenyl]-, hydrochloride (1:2), TIP60i

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Size/SKUAvailabilityPrice
5 mg

Estimated to ship onSeptember 08, 2026fromMILWAUKEE

$157.00
25 mg

Estimated to ship onSeptember 08, 2026fromMILWAUKEE

$630.00

About This Item

Empirical Formula (Hill Notation):
C33H40N6O3 · 2HCl
CAS Number:
Molecular Weight:
641.63
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

$157.00

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Estimated to ship onSeptember 08, 2026Details


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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

H2O: 2 mg/mL, clear

storage temp.

−20°C

SMILES string

O=C(O)CN1N=C(C2=CC=C(CN(CCC3=CC=CC=C3)CCCCOC4=CC=C(CN5CCCC5)C=C4)C=C2)N=N1.[H]Cl.[H]Cl

InChI key

HYXIFSOROZPMMU-UHFFFAOYSA-N

Biochem/physiol Actions

Cell penetrant, potent and selective HAT Tip60 inhibitor
TH1834 is a cell penetrant, potent and selective histone acetyltransferase (HAT) Tip60 inhibitor that interact with active binding pocket of Tip60. TH1834 induces apoptosis and increased unrepaired DNA damage in breast and prostate cancer cell lines but not control MCF10A cells.

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This Item
SML1507PZ0234SML2281
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

solubility

H2O: 2 mg/mL, clear

solubility

H2O: 15 mg/mL, clear

solubility

H2O: 20 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

color

white to beige

color

white to beige

color

white to light brown

color

white to beige


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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