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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Available to ship TODAYfromMILWAUKEE | $56.80 $48.28 |
25 mg | Check Cart for Availability | $230.00 |
About This Item
Empirical Formula (Hill Notation):
C15H11Cl2NO4
CAS Number:
Molecular Weight:
340.16
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
$48.28
List Price$56.80Save 15%Web-Only Promotion
Available to ship TODAYDetails
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
Clc1c(cccc1)OCC(=O)Nc2c(ccc(c2)Cl)C(=O)O
InChI
1S/C15H11Cl2NO4/c16-9-5-6-10(15(20)21)12(7-9)18-14(19)8-22-13-4-2-1-3-11(13)17/h1-7H,8H2,(H,18,19)(H,20,21)
InChI key
CVQCJPCMPGKEDH-UHFFFAOYSA-N
Biochem/physiol Actions
CBA (Compound 5; 4-Chloro-2-[[2-(2-chlorophenoxy)acetyl]amino]benzoic acid) is a cell penetrant, potent and selective TRPM4 (Transient receptor potential melastatin member 4) inhibitor that shows not significant activity against TRPM5, TRPM7, TRPM8, TRPV1, TRPV3, TRPV6. It rescues functional expression of mutant A432T TRPM4 in cells. CBA (Compound 5) exhibits neuroprotective activity against glutamate-induced neurodegeneration.
cell penetrant, potent and selective TRPM4 (Transient receptor potential melastatin member 4) inhibitor
1 of 1
This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description - | description from rabbit, purified by affinity chromatography | description targeting mouse Trpm4 |
| form powder | form - | form - | form lyophilized powder |
| assay ≥98% (HPLC) | assay - | assay - | assay - |
| Quality Level 100 | Quality Level 200 | Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. -10 to -25°C | storage temp. - | storage temp. −20°C |
| solubility DMSO: 2 mg/mL, clear | solubility - | solubility - | solubility - |
| color white to beige | color - | color - | color - |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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