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SML2539

NAB-14

≥98% (HPLC)

Synonym(s):

Carbamic acid, N,N-diethyl-, 4-[(1H-indol-7-ylamino)carbonyl]phenyl ester

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Size/SKUAvailabilityPrice
5 mg

Available to ship TODAYfromMILWAUKEE

$117.00
25 mg

Available to ship TODAYfromMILWAUKEE

$493.00

About This Item

Empirical Formula (Hill Notation):
C20H21N3O3
CAS Number:
Molecular Weight:
351.40
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder

$117.00


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assay

≥98% (HPLC)

form

powder

color

white to gray

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

CCN(CC)C(OC(C=C1)=CC=C1C(NC2=C3C(C=CN3)=CC=C2)=O)=O

InChI

1S/C20H21N3O3/c1-3-23(4-2)20(25)26-16-10-8-15(9-11-16)19(24)22-17-7-5-6-14-12-13-21-18(14)17/h5-13,21H,3-4H2,1-2H3,(H,22,24)

InChI key

WCGIKJOMEYPSIP-UHFFFAOYSA-N

Biochem/physiol Actions

NAB-14 is a negative allosteric modulator (NAM) selective for GluN2C/2D-containing NMDA glutamate receptors. NAB-14 was >800-fold selective for recombinant GluN2C/GluN2D over GluN2A/GluN2B in Xenopus oocytes and exhibited an IC50 value of 580 nM at recombinant GluN1/GluN2D receptors.
Negative allosteric modulator selective for GluN2C/2D-containing NMDA receptors

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≥98% (HPLC)

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≥98% (HPLC)

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description

A zwitterionic amidosulfobetaine detergent useful for solubilizing proteins visualized by 2D-electrophoresis.

form

powder

form

powder

form

solid

form

solid

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥97% (HPLC)

assay

≥97% (HPLC)

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

10-30°C

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 10 mg/mL, pale yellow

solubility

water: 50 mg/mL

color

white to gray

color

white to light brown

color

yellow-white

color

white to off-white


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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