SML2535

MRK-740

≥98% (HPLC)

• Synonym(s): 4-(3-(3,5-Dimethoxy-phenyl)-1,2,4-oxadiazol-5-yl)-1-methyl-9-(2-methyl-pyridin-4-yl)-1,4,9-triaza-spiro[5.5]undecane
• Empirical Formula (Hill Notation): C₂₅H₃₂N₆O₃
• CAS Number: 2387510-80-5
• Molecular Weight: 464.56
• UNSPSC Code: 51111800
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Properties

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: CN1CCN(C2=NC(C3=CC(OC)=CC(OC)=C3)=NO2)CC14CCN(C5=CC(C)=NC=C5)CC4
• InChI: 1S/C25H32N6O3/c1-18-13-20(5-8-26-18)30-9-6-25(7-10-30)17-31(12-11-29(25)2)24-27-23(28-34-24)19-14-21(32-3)16-22(15-19)33-4/h5,8,13-16H,6-7,9-12,17H2,1-4H3
• InChI key: NZYTZRHHBAJPKN-UHFFFAOYSA-N

Description

Biochem/physiol Actions

MRK-740 is a cell penetrant, potent and selective inhibitor of PRDM9 that inhibits methylation of H3K4 in cells.

cell penetrant, potent and selective inhibitor of PRDM9

Safety Information

• Storage Class: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable