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SML2409

NITD008

≥98% (HPLC), falviviruses inhibitor, powder

Synonym(s):

7-(2-C-Ethynyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, 7-Deaza-2′-C-acetylene-adenosine, NITD 008

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Size/SKUAvailabilityPrice
5 mg
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$184.00
$191.00
25 mg
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$600.00
$510.00

About This Item

Empirical Formula (Hill Notation):
C13H14N4O4
CAS Number:
Molecular Weight:
290.27
NACRES:
NA.77
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

$191.00

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Product Name

NITD008, ≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear (warmed)

storage temp.

−20°C

SMILES string

NC1=C2C=CN(C2=NC=N1)[C@@H]3O[C@@H]([C@H]([C@](C#C)3O)O)CO

InChI

1S/C13H14N4O4/c1-2-13(20)9(19)8(5-18)21-12(13)17-4-3-7-10(14)15-6-16-11(7)17/h1,3-4,6,8-9,12,18-20H,5H2,(H2,14,15,16)/t8-,9-,12-,13-/m1/s1

InChI key

NKRAIOQPSBRMOV-NRMKKVEVSA-N

Biochem/physiol Actions

NITD008 is a selective inhibitor of flaviviruses including dengue virus (EC50 = 0.64 μM), hepatitis C virus and Zika virus, and has also been shown to inhibit tick-borne flaviviruses in vitro. NITD008 has been reported to inhibit RNA-dependent RNA polymerase (RdRp), an essential protein of RNA viruses.
Selective inhibitor of flaviviruses including dengue virus, hepatitis C virus, and Zika virus

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This Item
SML3200940496
description

≥98% (HPLC)

description

≥98% (HPLC)

description

powder, ≥99.9% trace metals basis, battery grade

form

powder

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥99.9% trace metals basis

storage temp.

−20°C

storage temp.

−20°C

storage temp.

-

solubility

DMSO: 2 mg/mL, clear (warmed)

solubility

DMSO: 2 mg/mL, clear

solubility

-

color

white to beige

color

white to beige

color

colorless


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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