Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Estimated to ship TODAYfromMILWAUKEE | $106.00 |
25 mg | Estimated to ship TODAYfromMILWAUKEE | $409.00 $347.65 |
About This Item
Empirical Formula (Hill Notation):
C10H4Cl4O2
CAS Number:
Molecular Weight:
297.95
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
assay
≥98% (HPLC)
form
powder
color
faint green to dark gray
solubility
DMSO: 2 mg/mL, clear (warmed)
storage temp.
−20°C
SMILES string
ClC(Cl)(Cl)C1=CC(C2=CC(Cl)=CC=C2O1)=O
InChI
1S/C10H4Cl4O2/c11-5-1-2-8-6(3-5)7(15)4-9(16-8)10(12,13)14/h1-4H
InChI key
NTDHYMSVCBGQJF-UHFFFAOYSA-N
Biochem/physiol Actions
ST034307 is a selective inhibitor of adenylyl cyclase 1 (AC1) with analgesic activity. Adenylyl cyclase 1 has been shown to be a potential target for treating pain and reducing the dependency on opioids, but it has been difficult to inhibit AC1 selectively without also inhibiting other isoforms vital to physiological functions. ST034307 is selective for AC1 over all eight other adenylyl cyclase isoforms. It inhibited AC1 and reduced cAMP, while leaving AC8 unaffected and was shown to reduce pain in a mouse inflammatory pain model.
Selective inhibitor of adenylyl cyclase 1 (AC1) with analgesic activity
1 of 1
This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description ≥98% (HPLC) | description ≥98% (HPLC) | description ≥98% (HPLC) |
| form powder | form powder | form powder | form powder |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| storage temp. −20°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility DMSO: 2 mg/mL, clear (warmed) | solubility DMSO: 10 mg/mL, clear | solubility DMSO: 2 mg/mL, clear | solubility DMSO: 2 mg/mL, clear (warmed) |
| color faint green to dark gray | color white to beige | color white to beige | color white to beige |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.



