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Key Documents

SML1773

Sigma-Aldrich

TYFAVLM trifluoroacetate salt

≥98% (HPLC)

Synonym(s):

P7, Thr-Tyr-Phe-Ala-Val-Leu-Met trifluoroacetate salt, synthetic P7 peptide agonist trifluoroacetate salt

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About This Item

Empirical Formula (Hill Notation):
C41H61N7O10S · xC2HF3O2
Molecular Weight:
844.03 (free base basis)
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

assay

≥98% (HPLC)

form

lyophilized powder

storage condition

protect from light

color

white

shipped in

wet ice

storage temp.

−20°C

Biochem/physiol Actions

TYFAVLM/P7, a synthetic peptides comprising adhesion GPR56 β-strand-13 stalk, is a potent and selective agonist of GPR56. TYFAVLM activates GPR56 in cells.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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Oladapo E Olaniru et al.
Molecular metabolism, 53, 101285-101285 (2021-07-06)
Members of the adhesion G protein-coupled receptor (aGPCR) subfamily are important actors in metabolic processes, with GPR56 (ADGRG1) emerging as a possible target for type 2 diabetes therapy. GPR56 can be activated by collagen III, its endogenous ligand, and by

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