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SML1467

ASP7663

≥98% (HPLC)

Synonym(s):

(2E)-2-[7-Fluoro-1,2-dihydro-1-(2-methylpropyl)-2-oxo-3H-indol-3-ylidene]acetic acid, (E)-[7-Fluoro-1-(2-methylpropyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]acetic acid

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Size/SKUAvailabilityPrice
5 mg
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$149.00
25 mg

Available to ship TODAYfromMILWAUKEE

$451.00

About This Item

Empirical Formula (Hill Notation):
C14H14FNO3
CAS Number:
Molecular Weight:
263.26
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder

$149.00


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Quality Segment

assay

≥98% (HPLC)

form

powder

color

light orange to dark orange

solubility

DMSO: 25 mg/mL, clear

storage temp.

2-8°C

SMILES string

CC(C)CN(C1=C(F)C=CC=C1/C2=C\C(O)=O)C2=O

InChI

1S/C14H14FNO3/c1-8(2)7-16-13-9(4-3-5-11(13)15)10(14(16)19)6-12(17)18/h3-6,8H,7H2,1-2H3,(H,17,18)/b10-6+

InChI key

RCVZUIGCNAAMIC-UXBLZVDNSA-N

Biochem/physiol Actions

ASP7663 is a selective activator of transient receptor potential ankyrin 1 (TRPA1), known to play a role for chemical sensing in the pain pathway. ASP7663 activated human, rat, and mouse TRPA1 receptors with EC50 values of 510, 540, and 500 nM, respectively, and little or no affinity at more than 60 other related receptors, channels and enzymes. ASP7663 enhanced colonic motility and exerted analgesic effects against abdominal pain in mouse models.
ASP7663 is a selective activator of transient receptor potential ankyrin 1 (TRPA1).

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This Item
A7232EMU061121ABN1009
description

≥98% (HPLC)

description

≥98% (HPLC), solid

description

targeting mouse Trpa1

description

from rabbit, purified by affinity chromatography

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

-

assay

-

form

powder

form

solid

form

lyophilized powder

form

-

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

-

solubility

DMSO: 25 mg/mL, clear

solubility

DMSO: >10 mg/mL

solubility

-

solubility

-

color

light orange to dark orange

color

white to off-white

color

-

color

-


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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