Unfortunately, the stability of this product upon reconstitution has not been determined. It is recommended to use freshly prepared solutions. This product is shipped at ambient temperature during transport. However, for long-term storage, the powder form is maintained at 2-8°C. Please see the links below to publications reporting the stability of this material in solution:
https://pubmed.ncbi.nlm.nih.gov/20811032/
https://pubmed.ncbi.nlm.nih.gov/19108795/
SML1220
Doripenem hydrate
≥98% (HPLC), Ultra-broad spectrum carbapenem antibiotic, powder
Synonym(s):
(4R,5S,6S)-3-[[(3S,5S)-5-[[(Aminosulfonyl)amino]methyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid hydrate
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| Size/SKU | Availability | Price |
|---|---|---|
10 mg | Check Cart for Availability | $134.00 |
50 mg | Check Cart for Availability | $527.00 |
About This Item
Empirical Formula (Hill Notation):
C15H24N4O6S2 · H2O
CAS Number:
Molecular Weight:
438.52
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Product Name
Doripenem hydrate, ≥98% (HPLC)
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
H2O: 5 mg/mL, clear (warmed)
storage temp.
2-8°C
SMILES string
[S](=O)(=O)(NC[C@H]1NC[C@H](C1)SC2=C(N3[C@H]([C@H]2C)[C@H](C3=O)[C@H](O)C)C(=O)O)N.O
InChI
1S/C15H24N4O6S2.H2O/c1-6-11-10(7(2)20)14(21)19(11)12(15(22)23)13(6)26-9-3-8(17-5-9)4-18-27(16,24)25;/h6-11,17-18,20H,3-5H2,1-2H3,(H,22,23)(H2,16,24,25);1H2/t6-,7-,8+,9+,10-,11-;/m1./s1
InChI key
NTUBEBXBDGKBTJ-WGLOMNHJSA-N
Biochem/physiol Actions
Doripenem is an ultra-broad spectrum carbopenem antibiotic.
Doripenem is an ultra-broad spectrum carbopenem antibiotic. Doripenem is active against both gram-positive and gram-negative bacteria.
Doripenem hydrate is used to treat complicated urinary infection including Pyelonephritis caused by E.coli. Doripenem hydrate is promoted in the United States as DORIBAX®. This drug is synthesized from p-nitrobenzyl-protected enolphosphate 2b and N-(p-nitrobenzyloxycarbonyl)-protected aminomethylpyrrolidine.
Legal Information
DORIBAX is a registered trademark of Shionogi Inc.
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This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description VETRANAL®, analytical standard | description ≥98% (HPLC) | description 88052057, IHW Number: 9057, NOTE: Both the cell line and DNA from the cell line may be available for this product. Please choose -1VL or VIAL for cells, or -DNA-5UG for DNA. |
| form powder | form - | form powder | form - |
| assay ≥98% (HPLC) | assay - | assay ≥98% (HPLC) | assay - |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level - |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. −20°C | storage temp. -140 to -196°C |
| solubility H2O: 5 mg/mL, clear (warmed) | solubility - | solubility H2O: ≥20 mg/mL | solubility - |
| color white to beige | color - | color white to light brown | color - |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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May I enquire on the recommended storage condition of the reconstituted working solution and the estimated shelf life of both the neat and working solution? Is there also a recommended transport temperature for the product?
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