Skip to Content
MilliporeSigma

Skip To

SML1064

IMM-01

≥98% (HPLC)

Promotion Available

Synonym(s):

2-[(2,4-Dihydroxyphenyl)methylene]-N-(1,1-dimethylethyl)-hydrazinecarbothioamide, Intramimic-01, N1-(tert-Butyl)-2-(2,4-dihydroxybenzylidene)hydrazine-1-carbothioamide

Sign In to View Organizational & Contract Pricing.

Spend $500 — Save 5%; Spend $750 — Save 10%; Spend $1,000 — Save 22%*

Sign in to check eligibility. Shop Products

Select a Size

Change View
Size/SKUAvailabilityPrice
5 mg
Check Cart for Availability
$131.00

About This Item

Empirical Formula (Hill Notation):
C12H17N3O2S
CAS Number:
Molecular Weight:
267.35
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder

$131.00

Save Up To 22%


Check Cart for Availability

​
Request a Custom Order
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to light brown

solubility

DMSO: 10 mg/mL, clear

storage temp.

2-8°C

SMILES string

S=C(N\N=C\c1c(cc(cc1)O)O)NC(C)(C)C

InChI

1S/C12H17N3O2S/c1-12(2,3)14-11(18)15-13-7-8-4-5-9(16)6-10(8)17/h4-7,16-17H,1-3H3,(H2,14,15,18)/b13-7+

InChI key

LTFUAYRGVLQXKC-NTUHNPAUSA-N

Application

IMM-01 has been used as a formin activator to study its effects on motor neurons (MNs).

Biochem/physiol Actions

IMM-01 is an agonist of the mammalian Diaphanous (mDia)-related formins that triggers actin assembly and microtubule stabilization, serum response factor-mediated gene expression, cell-cycle arrest, and apoptosis. IMM-01 inhibits DID–DAD binding, which in turn activates mDia family of formins in cells. IMM-01 slows tumor growth in a mouse xenograft model of colon cancer.
IMM-01 is an agonist of the mammalian Diaphanous (mDia)-related formins that triggers actin assembly.
IMM-01 binds and activates formin thereby leading to autoinhinition.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
SML1604A2731SML1970
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC), powder

description

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 10 mg/mL, clear

solubility

DMSO: 10 mg/mL, clear

solubility

DMSO: >5 mg/mL

solubility

DMSO: 2 mg/mL, clear

color

white to light brown

color

white to beige

color

white to beige

color

light yellow to dark orange


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library




Questions

Reviews

No rating value

Active Filters