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SML0412

IM-54

≥98% (HPLC)

Synonym(s):

1-Methyl-3-(1-methyl-1H-indol-3-yl)-4-(pentylamino)-1H-pyrrole-2,5-dione, 2-(1H-Indol-3-yl)-3-pentylamino-maleimide

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Size/SKUAvailabilityPrice
5 mg
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$218.00

About This Item

Empirical Formula (Hill Notation):
C19H23N3O2
CAS Number:
Molecular Weight:
325.40
UNSPSC Code:
12352200
MDL number:
NACRES:
NA.77
PubChem Substance ID:
Assay:
≥98% (HPLC)
Form:
powder

$218.00


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Quality Segment

assay

≥98% (HPLC)

form

powder

color

light orange to dark orange

solubility

DMSO: 5 mg/mL (clear solution)

storage temp.

2-8°C

SMILES string

CCCCCNC1=C(C(=O)N(C)C1=O)c2cn(C)c3ccccc23

InChI

1S/C19H23N3O2/c1-4-5-8-11-20-17-16(18(23)22(3)19(17)24)14-12-21(2)15-10-7-6-9-13(14)15/h6-7,9-10,12,20H,4-5,8,11H2,1-3H3

InChI key

SGLOMINNEBLJFF-UHFFFAOYSA-N

Biochem/physiol Actions

IM-54 is a cell permeable, potent and selective inhibitor of necrosis.
IM-54 is a cell permeable, potent and selective inhibitor of necrosis. The compound inhibits necrosis induced by oxidative stress. IM-54 does not inhibit apoptosis induced by anticancer drugs.

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This Item
480060
description

≥98% (HPLC)

description

The Necrosis Inhibitor, IM-54, also referenced under CAS 861891-50-1, selectively blocks oxidative stress-induced necrotic cell death. This small molecule/inhibitor is primarily used for Cancer applications.

form

powder

form

solid

assay

≥98% (HPLC)

assay

≥95% (HPLC)

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 5 mg/mL (clear solution)

solubility

methanol: 10 mg/mL, DMSO: 100 mg/mL

color

light orange to dark orange

color

yellow-orange


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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