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About This Item
Empirical Formula (Hill Notation):
C27H39N7O10
Molecular Weight:
621.64
UNSPSC Code:
12352200
NACRES:
NA.32
Recommended Products
assay
≥95% (HPLC)
form
lyophilized
composition
Peptide Content, ≥75%
storage condition
protect from light
storage temp.
−20°C
Amino Acid Sequence
Ac-Val-Gln-Val-Asp-pNA
Application
Ac-VQVD-pNa (Acetyl-Val-Gln-Val-Asp-p-nitroanilide) is used as a chromogenic caspase substrate.
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Bin Fang et al.
Journal of molecular biology, 360(3), 654-666 (2006-06-20)
The molecular basis for the substrate specificity of human caspase-3 has been investigated using peptide analog inhibitors and substrates that vary at the P2, P3, and P5 positions. Crystal structures were determined of caspase-3 complexes with the substrate analogs at
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