SAB5703037

Anti-Phospho-BRD4(pSer1083) Antibody, clone 5B6X4, Rabbit Monoclonal

• Synonym(s): BRD4, CAP, HUNK1, HUNKI, MCAP, bromodomain containing 4
• UNSPSC Code: 12352203
• NACRES: NA.46

Properties

• biological source: rabbit
• Quality Level: 100
• material: colorless
• clone: 5B6X4, monoclonal
• form: liquid
• mol wt: 200 kDa
• species reactivity: human
• concentration: 1mg/mL
• technique(s): western blot: 1:100 - 1:500
• color: colorless
• isotype: IgG
• immunogen sequence: HQSPP
• UniProt accession no.: O60885
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... BRD4(23476)

Description

General description

The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.

Immunogen

A synthetic phosphorylated peptide around S1083 of human BRD4 (NP_490597.1).

PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.

Application

WB

Safety Information

• Pictograms: GHS07,GHS09
• signalword: Warning
• hcodes: H317,H411
• pcodes: P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
• Hazard Classifications: Aquatic Chronic 2 - Skin Sens. 1
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3