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SFK1

Name: SFK1
Brand: SIGMA

≥98% (HPLC), solid

Synonym(s):

Cyclohexylmethyl 4-[imino(octylamino)methyl]benzoate hydrochloride, Suppressor of FK-506 1

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About This Item

Empirical Formula (Hill Notation):

C₂₃H₃₇ClN₂O₂

CAS Number:

678997-25-6

Molecular Weight:

409.01

NACRES:

NA.77

PubChem Substance ID:

24724612

UNSPSC Code:

51111800

MDL number:

MFCD06412465

Assay:

≥98% (HPLC)

Form:

solid

Storage condition:

desiccated

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Properties

Quality Segment

100

assay

≥98% (HPLC)

form

solid

storage condition

desiccated

solubility

DMSO: 12 mg/mL

storage temp.

2-8°C

SMILES string

Cl[H].CCCCCCCCNC(=N)c1ccc(cc1)C(=O)OCC2CCCCC2

InChI

1S/C23H36N2O2.ClH/c1-2-3-4-5-6-10-17-25-22(24)20-13-15-21(16-14-20)23(26)27-18-19-11-8-7-9-12-19;/h13-16,19H,2-12,17-18H2,1H3,(H2,24,25);1H

InChI key

URYYYIJUCLTKBY-UHFFFAOYSA-N

Description

Application

SFK1 may be used in cell signaling studies.

Biochem/physiol Actions

SFK1 interacts directly with yeast mitochodria. Induces cell death in low salt conditions and suppresses the ability of FK506 to inhibit cell growth in the presence of high levels of NaCl.

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This Item	342500	SML2746	S1697
Sigma-Aldrich S5071 SFK1	Sigma-Aldrich 342500 FK-506, Streptomyces sp.	Sigma-Aldrich SML2746 SRS11-92	Sigma-Aldrich S1697 SPD304
description ≥98% (HPLC), solid	description Immunosuppressant that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2.	description ≥98% (HPLC)	description ≥98% (HPLC), solid
assay ≥98% (HPLC)	assay ≥98% (TLC)	assay ≥98% (HPLC)	assay ≥98% (HPLC)
form solid	form solid	form powder	form solid
Quality Level 100	Quality Level -	Quality Level 100	Quality Level 100
storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C
solubility DMSO: 12 mg/mL	solubility DMSO: 10 mg/mL, methanol: 5 mg/mL	solubility DMSO: 2 mg/mL, clear	solubility H₂O: >5 mg/mL
storage condition desiccated	storage condition OK to freeze, desiccated	storage condition -	storage condition -

pictograms

GHS05

signalword

Danger

hcodes

H318

pcodes

P280 - P305 + P351 + P338

Hazard Classifications

Eye Dam. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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