This material includes a proprietary 20 amino acids tag before the first Met. The calculated molecular weight is not available. However, in SDS-PAGE gels, this product runs at approximately 15 - 20 kDa as shown below.
S1071
α-Synuclein A53T human
recombinant, expressed in E. coli, N-terminal histidine tagged, ≥90% (SDS-PAGE), lyophilized powder
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| Size/SKU | Availability | Price |
|---|---|---|
500 μg | Check Cart for Availability | $776.00 |
About This Item
recombinant
expressed in E. coli
Quality Segment
assay
≥90% (SDS-PAGE)
form
lyophilized powder
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... SNCA(6622)
General description
Application
Biochem/physiol Actions
α-Synuclein (α-Syn) interacts with toll-like receptor 2 (TLR2) and mediates interleukin-1β (IL-1β) synthesis.
A point mutation in the α-synuclein gene, A53T (Ala53-Thr), is linked to familial Parkinson′s disease.
A point mutation in the α-synuclein gene, A53T (Ala53-Thr), is linked to familial Parkinson′s disease. Mice expressing A53T human α-synuclein, but not wild-type or the A30P variants, develop adult-onset neurodegenerative disease with a progressive motoric dysfunction leading to death.
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This Item | |||
|---|---|---|---|
| description recombinant, expressed in E. coli, N-terminal histidine tagged, ≥90% (SDS-PAGE), lyophilized powder | description recombinant, expressed in E. coli, N-terminal histidine tagged, ≥90% (SDS-PAGE), lyophilized powder | description serum, Chemicon® | description clone 81A, from mouse |
| assay ≥90% (SDS-PAGE) | assay ≥90% (SDS-PAGE) | assay - | assay - |
| recombinant expressed in E. coli | recombinant expressed in E. coli | recombinant - | recombinant - |
| Quality Level 200 | Quality Level 200 | Quality Level 100 | Quality Level 100 |
| form lyophilized powder | form lyophilized powder | form - | form - |
| shipped in dry ice | shipped in dry ice | shipped in dry ice | shipped in dry ice |
| storage temp. −20°C | storage temp. −20°C | storage temp. - | storage temp. - |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
Eyeshields, Gloves, type N95 (US)
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what is it molecular weight?
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