PLA0074

Rabbit anti-BARD1 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

• Synonym(s): BARD-1, BRCA1-associated RING domain gene 1
• NACRES: NA.41
• UNSPSC Code: 12352203
• Conjugate: unconjugated
• Clone: polyclonal
• Application: IP, WB
• Citations: -

Properties

• biological source: rabbit
• Quality Segment: 100
• conjugate: unconjugated
• antibody form: affinity purified immunoglobulin
• antibody product type: primary antibodies
• clone: polyclonal
• species reactivity: human
• technique(s): immunoprecipitation (IP): 2-10 μg/mg, western blot: 1:500-1:2,500
• accession no.: NP_000456.1
• UniProt accession no.: Q99728
• shipped in: wet ice
• storage temp.: 2-8°C
• target post-translational modification: unmodified
• Gene Information: rabbit ... BARD1(580)

Description

Immunogen

The epitope recognized by PLA0074 maps to a region between residues 250 and 300 of human BRCA1-associated RING Domain 1 using the numbering given in entry NP_000456.1 (GeneID 580).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide

Other Notes

BRCA1 associated RING domain 1 (BARD1) together with BRCA1 is an E3 ubiquitin ligase. BARD1/BRCA1 has been shown to ubiquinate RNA polymerase II in response to DNA damage. BARD1/BRCA1 ubiquitin ligase activity has also been shown to be important in the prevention of double stranded breaks and the regulation of centrosome number.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable