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P3755

6-Propyl-2-thiouracil

≥99% (HPLC), powder

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Synonym(s):

2,3-Dihydro-6-propyl-2-thioxo-4(1H)-pyrimidinone, 4-Hydroxy-2-mercapto-6-propylpyrimidine

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Size/SKUAvailabilityPrice
10 g

Available to ship TODAYfromMILWAUKEE

$64.80
25 g

Estimated to ship onSeptember 28, 2026fromMILWAUKEE

$101.00
100 g

Available to ship TODAYfromMILWAUKEE

$326.00

About This Item

Empirical Formula (Hill Notation):
C7H10N2OS
CAS Number:
51-52-5
Molecular Weight:
170.23
NACRES:
NA.51
PubChem Substance ID:
24898446
UNSPSC Code:
41106305
EC Number:
200-103-2
MDL number:
MFCD00006041
Beilstein/REAXYS Number:
130039
Assay:
≥99% (HPLC)
Form:
powder
Solubility:
10% NH3: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow

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Product Name

6-Propyl-2-thiouracil, enzyme inhibitor

Quality Segment

200

assay

≥99% (HPLC)

form

powder

mp

218-220 °C (lit.)

solubility

10% NH3: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow

SMILES string

CCCC1=CC(=O)NC(=S)N1

InChI

1S/C7H10N2OS/c1-2-3-5-4-6(10)9-7(11)8-5/h4H,2-3H2,1H3,(H2,8,9,10,11)

InChI key

KNAHARQHSZJURB-UHFFFAOYSA-N

Gene Information

human ... DIO1(1733), TPO(7173)

General description

6-Propyl-2-thiouracil or 6-n-Propylthiouracil (PROP) is a compound with a bitter taste.

Application

6-Propyl-2-thiouracil (PROP) has been used to impregnate on disk for PROP taster status studies for sensory characterization in a defined human sample group. It has been used as a screening agent for testing the intensity of taste by labeled magnitude scale (LMS).
6-Propyl-2-thiouracil is a thyreostatic (thyroid hormone) agent that may be used as a reference material in thyreostatic drug separation and detection technologies such as capillary electrophoresis, high performance liquid chromatography (HPLC), or gas chromatography.

Biochem/physiol Actions

6-Propyl-2-thiouracil (6-PTU), a potential inhibitor of D1 iodothyronine deiodinase, is involved in the deiodination of iodothyronines. It is an uncompetitive inhibitor of iodothyronine substrates.

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This Item
P3700000PHR260946698
6-Propyl-2-thiouracil enzyme inhibitor

Sigma-Aldrich

P3755

6-Propyl-2-thiouracil

Propylthiouracil European Pharmacopoeia (EP) Reference Standard

P3700000

Propylthiouracil

Propylthiouracil Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR2609

Propylthiouracil

6-Propyl-2-thiouracil VETRANAL®, analytical standard

Supelco

46698

6-Propyl-2-thiouracil

description

enzyme inhibitor

description

European Pharmacopoeia (EP) Reference Standard

description

Pharmaceutical Secondary Standard; Certified Reference Material

description

VETRANAL®, analytical standard

Quality Level

200

Quality Level

-

Quality Level

300

Quality Level

200

form

powder

form

-

form

solid

form

-

assay

≥99% (HPLC)

assay

-

assay

-

assay

-

solubility

10% NH3: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow

solubility

-

solubility

-

solubility

-

mp

218-220 °C (lit.)

mp

218-220 °C (lit.)

mp

218-220 °C (lit.)

mp

218-220 °C (lit.)

Gene Information

human ... DIO1(1733), TPO(7173)

Gene Information

human ... DIO1(1733), TPO(7173)

Gene Information

-

Gene Information

human ... DIO1(1733), TPO(7173)

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pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

hcodes

H302,H351

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

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    Certificates of Analysis (COA)

    Lot/Batch Number
    BCCN3339
    063K0144
    052H2511
    056K2512
    047H2500

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