P0022
PS48
≥98% (HPLC)
Synonym(s):
5-(4-Chloro-phenyl)-3-phenyl-pent-2-enoic acid
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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Available to ship TODAYfromMILWAUKEE | $153.00 |
25 mg | Available to ship TODAYfromMILWAUKEE | $613.00 |
About This Item
Empirical Formula (Hill Notation):
C17H15ClO2
CAS Number:
Molecular Weight:
286.75
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
protect from light
Quality Segment
assay
≥98% (HPLC)
form
powder
storage condition
protect from light
color
white to off-white
solubility
DMSO: >20 mg/mL
storage temp.
2-8°C
SMILES string
OC(=O)\C=C(\CCc1ccc(Cl)cc1)c2ccccc2
InChI
1S/C17H15ClO2/c18-16-10-7-13(8-11-16)6-9-15(12-17(19)20)14-4-2-1-3-5-14/h1-5,7-8,10-12H,6,9H2,(H,19,20)/b15-12-
InChI key
LLJYFDRQFPQGNY-QINSGFPZSA-N
Biochem/physiol Actions
PDK1 (phosphoinositide-dependent protein kinase 1) activator which binds to the HM/PIF binding pocket rather than the ATP-binding site.
PS48 is a PDK1 (phosphoinositide-dependent protein kinase 1) activator which binds to the HM/PIF binding pocket rather than the ATP-binding site. PS48 is one of only a few truly allosteric compounds targeting a regulatory binding site on a protein kinase catalytic domain that is not adjacent to or overlapping with the ATP-binding site.
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This Item | ||
|---|---|---|
| description ≥98% (HPLC) | description ≥98% (HPLC) | description targeting mouse Pdk1 |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay - |
| form powder | form - | form lyophilized powder |
| Quality Level 100 | Quality Level - | Quality Level 100 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. −20°C |
| solubility DMSO: >20 mg/mL | solubility DMSO: 2 mg/mL, clear | solubility - |
| storage condition protect from light | storage condition - | storage condition - |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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