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N7252

Sigma-Aldrich

19-Nortestosterone

Synonym(s):

17β-Hydroxy-19-norandrost-4-en-3-one, 17β-Hydroxy-4-estren-3-one, 19-Norandrostenolone, 4-Estren-17β-ol-3-one, Nadrolone, Nandrolone

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About This Item

Empirical Formula (Hill Notation):
C18H26O2
CAS Number:
434-22-0
Molecular Weight:
274.40
Beilstein/REAXYS Number:
2055849
EC Number:
207-101-0
MDL number:
MFCD00003664
UNSPSC Code:
51111800
PubChem Substance ID:
24897817
NACRES:
NA.77

biological source

synthetic (organic)

Quality Level

200

sterility

non-sterile

assay

≥98% (TLC)

form

powder

drug control

USDEA Schedule III; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada

solubility

chloroform: 50 mg/mL, clear, colorless to light yellow

shipped in

ambient

storage temp.

room temp

SMILES string

C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@H]34)[C@@H]1CC[C@@H]2O

InChI

1S/C18H26O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h10,13-17,20H,2-9H2,1H3/t13-,14+,15+,16-,17-,18-/m0/s1

InChI key

NPAGDVCDWIYMMC-IZPLOLCNSA-N

Gene Information

human ... SERPINA6(866) , SHBG(6462)
rat ... Ar(24208) , Nr3c2(25672) , Pgr(25154)

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Biochem/physiol Actions

19-Nortestosterone (nandrolone) is an anabolic steriod hormone that acts as an androgen receptor (AR) agonist.

pictograms

Health hazard
GHS08

signalword

Danger

Hazard Classifications

Carc. 2 - Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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P Kintz et al.
Journal of pharmaceutical and biomedical analysis, 24(5-6), 1125-1130 (2001-03-15)
A sensitive, specific and reproducible method for the quantitative determination of nandrolone in human hair has been developed. The sample preparation involved a decontamination step of the hair with methylene chloride. The hair sample (about 100 mg) was solubilized in
Pieter Van Renterghem et al.
Analytica chimica acta, 768, 41-48 (2013-03-12)
Due to their performance enhancing properties, use of anabolic steroids (e.g. testosterone, nandrolone, etc.) is banned in elite sports. Therefore, doping control laboratories accredited by the World Anti-Doping Agency (WADA) screen among others for these prohibited substances in urine. It
J Segura et al.
Forensic science international, 107(1-3), 347-359 (2000-02-26)
Detection of anabolic steroids in hair samples has been possible only in fatal cases or in cases of high-continuous dosages. In order to verify the possibility of detecting an acute administration, a sensitive and specific assay has been developed for
R M N Kohler et al.
British journal of sports medicine, 36(5), 325-329 (2002-09-28)
The aim of this review is to analyse the studies on nandrolone metabolism to determine if it is possible for an athlete to test positive for nandrolone without having ingested or injected nandrolone.
A Farjam et al.
Analytical chemistry, 63(21), 2481-2487 (1991-11-01)
An immunoaffinity precolumn containing immobilized antibodies raised against the synthetic steroid hormone beta-19-nortestosterone, has been used for the automated sample pretreatment of urine samples containing beta-19-nortestosterone or the related steroids norethindrone and norgestrel. The sample pretreatment system was coupled on-line
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