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M8527

4-Methylumbelliferyl α-L-fucopyranoside

fluorogenic, ≥97% (TLC), powder

Synonym(s):

4-Methylumbelliferyl alpha-L-fucopyranoside

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1 mg

Available to ship TODAYfromMILWAUKEE

$225.00
5 mg

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$730.00
10 mg

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$1,410.00
25 mg

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$2,920.00
100 mg

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$8,480.00
$7,208.00

About This Item

Empirical Formula (Hill Notation):
C16H18O7
CAS Number:
54322-38-2
Molecular Weight:
322.31
NACRES:
NA.21
PubChem Substance ID:
24897268
UNSPSC Code:
12352204
EC Number:
259-098-0
MDL number:
MFCD00051218
Beilstein/REAXYS Number:
8160514

$225.00

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Product Name

4-Methylumbelliferyl α-L-fucopyranoside, ≥97% (TLC)

Quality Level

200

assay

≥97% (TLC)

form

powder

solubility

DMF: 100 mg/mL, clear, colorless to faintly yellow

fluorescence

λex 360 nm; λem 449 nm (Reaction product)

storage temp.

−20°C

SMILES string

C[C@@H]1O[C@@H](Oc2ccc3C(C)=CC(=O)Oc3c2)[C@@H](O)[C@H](O)[C@@H]1O

InChI

1S/C16H18O7/c1-7-5-12(17)23-11-6-9(3-4-10(7)11)22-16-15(20)14(19)13(18)8(2)21-16/h3-6,8,13-16,18-20H,1-2H3/t8-,13+,14+,15-,16-/m0/s1

InChI key

CQKHENXHLAUMBH-CRLRYRHBSA-N

General description

Substrate for α-L-fucosidase

Application

4-Methylumbelliferyl α-L-fucopyranoside has been used:
  • as a substrate in α-L-fucosidase 1 (α-L-FUCA-1) enzyme assays to convert it to the fluorescent product 4-methylumbelliferone (4MU) for finding the distribution of the membrane-associated α-L-FUCA-1 of human sperm[1]
  • as a fluorogenic substrate in enzyme assays to evaluate the stability of both the seminal plasma and membrane-associated α-l-fucosidase[2]
  • as a substrate to measure the enzymatic activity of α-L-FUCA-1 of cell extracts from TPC-1, BCPAP, 8505C, and CAL62 cell lines[3]

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This Item
M9766M0905M6018
4-Methylumbelliferyl α-L-fucopyranoside ≥97% (TLC)

Sigma-Aldrich

M8527

4-Methylumbelliferyl α-L-fucopyranoside

4-Methylumbelliferyl α-D-glucopyranoside α-glucosidase substrate

Sigma-Aldrich

M9766

4-Methylumbelliferyl α-D-glucopyranoside

4-Methylumbelliferyl β-D-mannopyranoside ≥98% (TLC)

Sigma-Aldrich

M0905

4-Methylumbelliferyl β-D-mannopyranoside

4-Methylumbelliferyl β-D-cellobioside glucanase substrate

Sigma-Aldrich

M6018

4-Methylumbelliferyl β-D-cellobioside

assay

≥97% (TLC)

assay

≥99% (TLC)

assay

≥98% (TLC)

assay

≥98.00% (TLC)

solubility

DMF: 100 mg/mL, clear, colorless to faintly yellow

solubility

pyridine: 50 mg/mL, clear, colorless to faintly yellow

solubility

pyridine: 10 mg/mL, clear, colorless to faintly yellow

solubility

water: 19.60-20.40 mg/mL, clear, colorless to faintly yellow

Quality Level

200

Quality Level

300

Quality Level

300

Quality Level

200

form

powder

form

powder

form

powder

form

powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

fluorescence

λex 360 nm; λem 449 nm (Reaction product)

fluorescence

-

fluorescence

-

fluorescence

-

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000508991
0000508984
0000508983
0000508983
0000508984

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A Giuliani et al.
Glycoconjugate journal, 10(6), 447-452 (1993-12-01)
The behaviour of a highly purified alpha-L-fucosidase (E.C. 3.2.1.51) extracted from octopus hepatopancreas was studied with phospholipid vesicles composed of phosphatidylcholine (PC) and phosphatidylserine (PS) containing the fucosylated ganglioside FucGM1, a potential natural substrate of the enzyme. The substrate recognition
Jennifer J Venditti et al.
Molecular reproduction and development, 74(6), 758-766 (2006-11-30)
Two distinctive isoforms of the enzyme alpha-L-fucosidase are found within human semen in substantial amounts, suggesting specialized functions during reproduction. The membrane-associated isozyme of human sperm cells was previously characterized biochemically, and here we report on its subcellular localization. Intact
Jennifer J Venditti et al.
International journal of andrology, 32(5), 556-562 (2008-06-05)
Previous reports from this laboratory documented the existence of two novel isoforms of alpha-L-fucosidase in human semen and showed that membrane-associated alpha-L-fucosidase is cryptically held within the acrosomal compartment and enriched within the sperm equatorial segment. The occurrence of these
View All Related Papers

Global Trade Item Number

SKUGTIN
M8527-100MG04061832909301
M8527-1MG04061826676196
M8527-5MG04061834063254
M8527-25MG04061832909325
M8527-10MG04061834063247

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