M6875

2-Mercaptopurine

≥95%, crystalline

• Synonym(s): 2-MP, 2-Purinethiol, 2-Thiopurine
• Empirical Formula (Hill Notation): C₅H₄N₄S
• CAS Number: 28128-19-0
• Molecular Weight: 152.18
• NACRES: NA.51
• PubChem Substance ID: 24897120
• UNSPSC Code: 41106305
• EC Number: 248-855-0
• MDL number: MFCD00047145
• eCl@ss: 32119108
• Assay: ≥95%
• Form: crystalline
• Solubility: 1 M NH4OH: 50 mg/mL, clear to slightly hazy, yellow to brown

Properties

• Quality Segment: 100
• assay: ≥95%
• form: crystalline
• color: yellow
• solubility: 1 M NH4OH: 50 mg/mL, clear to slightly hazy, yellow to brown
• SMILES string: [H]n1cnc2cnc(S)nc12
• InChI: 1S/C5H4N4S/c10-5-6-1-3-4(9-5)8-2-7-3/h1-2H,(H2,6,7,8,9,10)
• InChI key: HDBQZGJWHMCXIL-UHFFFAOYSA-N

Description

Application

2-Mercaptopurine (2-MP), a thiopurine and analog of the anti-cancer drug 6-mercaptopurine (6-MP), has been used to study the substrate and binding specificity and kinetics of xanthine oxidase-catalyzed hydroxylation and myeloperoxidase (MPO) reactions. 2-Mercaptopurine inhibited lipopolysacharide (LPS)-dependent nitric oxide (NO) production in B cells.

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Codes: H302,H318
• Precautionary Statements: P280 - P301 + P312 + P330 - P305 + P351 + P338 + P310
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1
• Storage Class: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• PPE (personal protective equipment): dust mask type N95 (US), Eyeshields, Faceshields, Gloves