M6309

Anti-Matrix Metalloproteinase-23, Hinge Region antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution

• Synonym(s): Anti-MMP-23
• UNSPSC Code: 12352203
• MDL number: MFCD03097011
• Conjugate: unconjugated
• Clone: polyclonal
• Application: ELISA (i), IHC (f), IP, WB
• Citations: 2

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous glycerol solution
• mol wt: antigen (active form) 45 kDa, antigen (pro-form) 58 kDa
• species reactivity: human
• concentration: ~1 mg/mL
• technique(s): immunohistochemistry (frozen sections): suitable, immunoprecipitation (IP): suitable, indirect ELISA: suitable, western blot: 1:1,000
• UniProt accession no.: P50281
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... MMP14(4323)

Description

General description

Matrix metalloproteinase-23B (MMP-23B) possesses regions which are rich in amino acids like proline and cysteine. The MMP-23B gene is localized on human chromosome 1p36.

Immunogen

synthetic peptide corresponding to the hinge region of human matrix metalloproteinase-23 (MIFR-2, CA-MMP).

Biochem/physiol Actions

Matrix metalloproteinase-23B (MMP-23B) is part of the matrix metalloproteinase family of proteins, which take part in the remodeling of the extracellular matrix.

Reacts with reduced and non-reduced MMP-23. Recognizes the pro-form and active forms of MMP-23 as well as a series of further cleaved active forms.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 50% glycerol and 15 mM sodium azide.