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L1567

Sigma-Aldrich

Lipoprotein, high density from human plasma

lyophilized powder

Synonym(s):

α-Lipoprotein, HDL, High density lipoprotein

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About This Item

CAS Number:
308068-14-6
MDL number:
MFCD00164407
UNSPSC Code:
12352202
NACRES:
NA.61

biological source

human plasma

Quality Level

200

assay

≥95% (agarose gel electrophoresis)

form

lyophilized powder

packaging

vial of ~10 mg protein (modified Lowry)

solubility

0.85% sodium chloride: soluble 10 mg/mL

UniProt accession no.

P02647
P02649
P02654
P02656
P04114
P06727
Q6Q788

storage temp.

2-8°C

Gene Information

human ... APOA1(335) , APOA4(337) , APOA5(116519) , APOB(338) , APOC1(341) , APOC3(345) , APOE(348)

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Biochem/physiol Actions

Lipids are transported in blood plasma among the various tissues by water-soluble complexes called lipoproteins, which differ in size as well as in their composition of lipids and proteins. Each lipoprotein complex contains a distinct number of apolipoproteins and lipid.

Physical form

Lyophilized from a solution of 0.15 M NaCl and 0.01% EDTA, pH 7.4

Other Notes

View more information on lipoprotein function and lipid transport at www.sigma-aldrich.com/enzymeexplorer.

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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[Personal requirements of nursing personnel].
B Sturm
Krankenpflege Journal, 26(12), 580-584 (1988-12-01)
Elizebeth C Turner et al.
Molecular biology of the cell, 22(15), 2664-2679 (2011-06-10)
Prostacyclin is increasingly implicated in re-endothelialization and angiogenesis but through largely unknown mechanisms. Herein the high-density lipoprotein (HDL) scavenger receptor class B, type 1 (SR-B1) adapter protein PDZ domain-containing protein 1 (PDZK1) was identified as an interactant of the human
Tao Tan et al.
Nature communications, 10(1), 3322-3322 (2019-07-28)
The tumor stromal microenvironments (TSM) including stromal cells and extracellular matrix (ECM) form an abominable barrier hampering nanoparticles accessibility to cancer cells, significantly compromising their antitumor effects. Herein, we report a bioinspired lipoprotein (bLP) that can induce efficient photothermia to
Shiyan Liu et al.
Nutrients, 15(9) (2023-07-11)
Sulforaphane (SFN), an isothiocyanate, is one of the major dietary phytochemicals found in cruciferous vegetables. Many studies suggest that SFN can protect against cancer and cardiometabolic diseases. Despite the proposed systemic and local vascular protective mechanisms, SFN's potential to inhibit
Kristina Ehring et al.
Journal of cell science, 135(5) (2021-07-27)
The Sonic hedgehog (Shh) pathway controls embryonic development and tissue homeostasis after birth. Long-standing questions about this pathway include how the dual-lipidated, firmly plasma membrane-associated Shh ligand is released from producing cells to signal to distant target cells and how

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Lipoproteins package cholesterol for transport in plasma, essential for lipid transport and cellular function in the body.

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