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K1127

Sigma-Aldrich

Kemptide acetate salt

≥95% (HPLC), powder

Synonym(s):

Phosphate acceptor peptide

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About This Item

Empirical Formula (Hill Notation):
C32H61N13O9 · xC2H4O2
CAS Number:
1629902-50-6
Molecular Weight:
771.91 (free base basis)
Beilstein/REAXYS Number:
6263936
UNSPSC Code:
12352200
PubChem Substance ID:
24896201

assay

≥95% (HPLC)

form

powder

color

white

solubility

H2O: 20 mg/mL

storage temp.

−20°C

SMILES string

CC(O)=O.[H]N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@@H](CO)C(N[C@@H](CC(C)C)C(NCC(O)=O)=O)=O)=O)C)=O)=O)=O

InChI

1S/C32H61N13O9.C2H4O2/c1-16(2)12-19(33)26(50)42-21(9-7-11-39-32(36)37)29(53)43-20(8-6-10-38-31(34)35)28(52)41-18(5)25(49)45-23(15-46)30(54)44-22(13-17(3)4)27(51)40-14-24(47)48;1-2(3)4/h16-23,46H,6-15,33H2,1-5H3,(H,40,51)(H,41,52)(H,42,50)(H,43,53)(H,44,54)(H,45,49)(H,47,48)(H4,34,35,38)(H4,36,37,39);1H3,(H,3,4)/t18-,19-,20-,21-,22-,23-;/m0./s1

InChI key

WRTDQEIEUYKAKV-PXILYFGCSA-N

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Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

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N-terminal protein sequencing for special applications.
Philip J Jackson
Methods in molecular biology (Clifton, N.J.), 211, 287-300 (2002-12-20)
L Belloni-Olivi et al.
The Biochemical journal, 315 ( Pt 2), 401-406 (1996-04-15)
In immature rat microvessels, endothelial cells and glioma cells, exposure to lead results in an increase in the level of protein kinase C in membranes. In this paper we have extended these studies to human erythrocytes and, in addition, studied
Masatake Sano et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 794(1), 149-156 (2003-07-31)
Micellar electrokinetic chromatography (MEKC) with laser-induced fluorescence (LIF) detection has been developed for a protein kinase assay. This protein kinase assay could readily determine the phosphorylation activity of substrate peptide kemptide using cAMP-dependent protein kinase (PKA) as a model enzyme.
Role of multiple basic residues in determining the substrate specificity of cyclic AMP-dependent protein kinase.
B E Kemp et al.
The Journal of biological chemistry, 252(14), 4888-4894 (1977-07-25)
G Tortora et al.
Proceedings of the National Academy of Sciences of the United States of America, 88(5), 2011-2015 (1991-03-01)
A marked decrease in the type I cAMP-dependent protein kinase regulatory subunit (RI alpha) and an increase in the type II protein kinase regulatory subunit (RII beta) correlate with growth inhibition and differentiation induced in a variety of types of
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