I9784

Monoclonal Anti-Insulin-like Growth Factor-II antibody produced in mouse

clone 75015, purified immunoglobulin, lyophilized powder

• Synonym(s): Anti-IGF2, Anti-INSIGF
• MDL number: MFCD00162567
• UNSPSC Code: 51111800
• NACRES: NA.41

Properties

• biological source: mouse
• Quality Level: 100
• conjugate: unconjugated
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: 75015, monoclonal
• form: lyophilized powder
• species reactivity: human
• technique(s): neutralization: suitable
• isotype: IgG1
• UniProt accession no.: P01344
• storage temp.: −20°C
• Gene Information: human ... IGF2(3481)

Description

Immunogen

purified, E. coli-derived recombinant human insulin-like growth factor-II.

Biochem/physiol Actions

Insulin-like growth factors -I and -II are important regulators of signaling that mediates growth and metabolism in cells. Insulin-like growth factor -II (IGF-II) is widely expressed during embryonic stages and regulates the placental development. IGF-II acts via specific receptor, IGF-IIR, the binding does not result in signal transduction, but is a mechanism to restrict the bioavailability of IGF-II. The effects of IGF-II signaling are important in growth of blood vessels (angiogenesis) gene transcription, proliferation and transformation.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)