I0274

myo-Inositol Monophosphatase from bovine brain

lyophilized powder, 5-20 units/mg protein

• Synonym(s): myo-Inositol monophosphate phosphohydrolase
• CAS Number: 37184-63-7
• EC Number: 3.1.3.25 (BRENDA, IUBMB)
• UNSPSC Code: 12352204
• MDL number: MFCD00679151

Properties

• form: lyophilized powder
• specific activity: 5-20 units/mg protein
• composition: Protein, ~0.5% Bradford
• storage temp.: −20°C

Description

Application

The enzyme plays a critical role in the recycling of inositol to phosphoinositides in the mammalian brain and participates in the phosphatidylinositol signaling pathway. It is inhibited non-competitively by Li⁺, which may be significant in the treatment of manic depression. The enzyme may help in identifying less toxic substitutes for lithium in manic depressive therapy.

Physical form

Lyophilized powder containing HEPES buffer salts, pH 7.5, and stabilizer

Other Notes

One unit will form 1.0 μmole of phosphate from inositol 1-phosphate per min at pH 7.4 at 37°C.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)