D6513

Desmosterol

≥84% (GC), cholesterol synthesis intermediate, powder

• Synonym(s): 24-Dehydrocholesterol, 3β-Hydroxy-5,24-cholestadiene, 5,24-Cholestadien-3β-ol
• Empirical Formula (Hill Notation): C₂₇H₄₄O
• CAS Number: 313-04-2
• Molecular Weight: 384.64
• NACRES: NA.77
• PubChem Substance ID: 24894033
• UNSPSC Code: 12352200
• EC Number: 206-236-2
• MDL number: MFCD00056432
• Assay: ≥84% (GC)
• Form: powder
• Quality level: 200

Properties

• Product Name: Desmosterol, ≥84% (GC)
• Quality Level: 200
• assay: ≥84% (GC)
• form: powder
• storage temp.: −20°C
• SMILES string: [H][C@@]12[C@]([C@](CC[C@H](O)C3)(C)C3=CC2)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCC=C(C)C
• InChI: 1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h7,9,19,21-25,28H,6,8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1
• InChI key: AVSXSVCZWQODGV-DPAQBDIFSA-N

Description

General description

Desmosterol is a C27 sterol intermediate in cholesterol synthesis. It may be associated with the pathogenesis of Alzheimer′s disease (AD).[1]

Application

Desmosterol has been used as a standard for the estimation of the concentrations of cholesterol and plant sterols. It has also been used to suppress nigericin-induced sterol regulatory element-binding proteins 2 (SREBP2) maturation.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)