D5764

2,3-Diphospho-D-glyceric acid pentasodium salt

Name: 2,3-Diphospho-<SC>D</SC>-glyceric acid pentasodium salt
Brand: SIGMA

glycolysis metabolite

Synonym(s):

2,3-DPG, D-Glycerate 2,3-diphosphate sodium salt

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About This Item

Linear Formula:

C₃H₃O₁₀P₂Na₅

CAS Number:

102783-53-9

Molecular Weight:

375.95

NACRES:

NA.25

PubChem Substance ID:

24893967

UNSPSC Code:

12352201

MDL number:

MFCD00070074

Key Documents

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biological source

synthetic

Quality Level

200

form

powder

impurities

3-phosphoglyceric acid, essentially free

color

white to off-white

solubility

water: 100 mg/mL, clear, colorless to faintly yellow

cation traces

Na: 24.5-32.5% (anhydrous)

storage temp.

−20°C

SMILES string

[Na].OC(=O)[C@@H](COP(O)(O)=O)OP(O)(O)=O

InChI

1S/C3H8O10P2.Na.H/c4-3(5)2(13-15(9,10)11)1-12-14(6,7)8;;/h2H,1H2,(H,4,5)(H2,6,7,8)(H2,9,10,11);;/t2-;;/m1../s1

InChI key

JJEMSNINYKJOBZ-YBBRRFGFSA-N

Related Categories

Biochemicals

Carbohydrates for Biochemical Research

Cell Culture Supplements & Reagents

Chemical Biology

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This Item	P8877	D9134	19710
Sigma-Aldrich D5764 2,3-Diphospho-D-glyceric acid pentasodium salt	Sigma-Aldrich P8877 D-(−)-3-Phosphoglyceric acid disodium salt	Sigma-Aldrich D9134 2,3-Diphospho-D-glyceric acid penta(cyclohexylammonium) salt	Sigma-Aldrich 19710 L-2-Phosphoglyceric acid disodium salt hydrate
biological source synthetic	biological source synthetic (inorganic)	biological source egg white	biological source -
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 100
solubility water: 100 mg/mL, clear, colorless to faintly yellow	solubility H₂O: 50 mg/mL, clear, colorless to faintly yellow	solubility H₂O: 50 mg/mL, clear, colorless to very faintly yellow	solubility -
form powder	form powder	form powder	form solid
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C
impurities 3-phosphoglyceric acid, essentially free	impurities <14% water (NMR)	impurities ≤1% 3-phosphoglyceric acid	impurities ≤0.2% P(i), ≤35% water

Application

D-Glycerate 2,3-diphosphate, cofactor of both phosphoglyceric acid mutase and hemoglobin, may be used as a reference compound in analysis of blood cell (erythrocyte) glycolysic cycle metabolites.

Biochem/physiol Actions

Metabolite of glycolysis within human erythrocytes produced by 2,3-diphosphoglycerate mutase in an alternative to the glycolytic pathway. Binds to hemaglobin to reduce oxygenation.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number

0000523445

0000523444

0000487506

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Temporary impact of blood donation on physical performance and hematologic variables in women.

Ida Stangerup et al.

Transfusion, 57(8), 1905-1911 (2017-04-30)

No former studies have examined how blood donation influences physical performance in women, who due to menstruation may have a slower recovery of performance. Therefore, the aim of this study was to clarify how VO VO VO VO

Surface-anchored framework for generating RhD-epitope stealth red blood cells.

Yueqi Zhao et al.

Science advances, 6(12), eaaw9679-eaaw9679 (2020-03-29)

Rhesus D (RhD) is one of the most important immunogenic antigens on red blood cells (RBCs). However, the supply of RhD-negative blood frequently faces critical shortages in clinical practice, and the positive-to-negative transition of the RhD antigen remains a great

Non-phthalate plasticizer DEHT preserves adequate blood component quality during storage in PVC blood bags.

Linda Larsson et al.

Vox sanguinis, 116(1), 60-70 (2020-09-13)

Commercial blood bags are predominantly made of polyvinyl chloride (PVC) plasticized with di(2-ethylhexyl) phthalate (DEHP). DEHP is favourable for storage of red blood cells (RBC). Historically, removal of DEHP from blood bags has been linked to unacceptable haemolysis levels. Oncoming

Restoration of Physiological Levels of Uric Acid and Ascorbic Acid Reroutes the Metabolism of Stored Red Blood Cells.

Manon Bardyn et al.

Metabolites, 10(6) (2020-06-04)

After blood donation, the red blood cells (RBCs) for transfusion are generally isolated by centrifugation and then filtrated and supplemented with additive solution. The consecutive changes of the extracellular environment participate to the occurrence of storage lesions. In this study

Storage of red blood cells in a novel polyolefin blood container: a pilot in vitro study.

H Gulliksson et al.

Vox sanguinis, 112(1), 33-39 (2016-12-22)

The present general plasticizer di-2-ethylhexyl-phthalate in polyvinylchloride (PVC) blood bags is only physically dispersed in PVC and will therefore leach into blood components. The objective of this study was to perform a first preliminary red blood cell (RBC) storage evaluation

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Global Trade Item Number

SKU	GTIN
D5764-100MG	04061832389042
D5764-25MG	04061833586761
D5764-500MG	04061832389066

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